Mixotrophic growth with acetate or volatile fatty acids maximizes growth and lipid production in Chlamydomonas reinhardtii

Moon, Myounghoon; Kim, Chul Woong; Park, Won Kun; Yoo, Gursong; Choi, Yoon E.; Yang, Ji Won

doi:10.1016/j.algal.2013.09.003

Cited by 139 publications

(63 citation statements)

References 33 publications

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“…Using mixotrophic algal species, different waste streams can be used for different phases of cultivation. During heterotrophic or mixotrophic cultivation, characterized by the formation of high densities of catalytically active algal biomass, carbon-, nitrogen-, and phosphaterich waste streams of various origins can be supplied [69]. The second phase of the cultivation, where generation of valued secondary metabolites occurs, provides a possibility of CO 2 mitigation from industrial effluent gases [54].…”

Section: Removal Of Eco-pollutants By the Action Of Microalgaementioning

confidence: 99%

Microalgae as versatile cellular factories for valued products

Koller

Muhr

Braunegg³

2014

Algal Research

498

307

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Section: Removal Of Eco-pollutants By the Action Of Microalgaementioning

confidence: 99%

Microalgae as versatile cellular factories for valued products

Koller

Muhr

Braunegg³

2014

Algal Research

498

307

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“…Also certain Chlorella species are known to grow on acetate as sole carbon source and produce various metabolites [54,58]. In those species, mixotrophic conditions usually favor the acetate uptake and biomass increase more than the heterotrophic ones [48]. This can be attributed to the ability of light to boost the biomass production of microalgae at the starting point of the culture, thus producing biomass and therefore accelerating the apparent heterotrophic uptake of VFA.…”

Section: Diverse Vfa As a Carbon Sourcementioning

confidence: 99%

“…Therefore, it is a general rule that a higher acetate proportion in the VFA mixture provides higher lipid accumulation and biomass growth. For example, both Chlamydomonas reinhardtii and Chlorella protothecoides were best cultivated in a mixture of acetic, propionic and butyric acid with a ratio of 8:1:1 [48,51]. Another usual ratio for microalgae cultivation, in which acetate is the most abundant acid, is 6:1:3 [53].…”

Section: Mixture Of Vfa As Carbon Sourcementioning

confidence: 99%

Utilization of Volatile Fatty Acids from Microalgae for the Production of High Added Value Compounds

et al. 2017

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Volatile Fatty Acids (VFA) are small organic compounds that have attracted much attention lately, due to their use as a carbon source for microorganisms involved in the production of bioactive compounds, biodegradable materials and energy. Low cost production of VFA from different types of waste streams can occur via dark fermentation, offering a promising approach for the production of biofuels and biochemicals with simultaneous reduction of waste volume. VFA can be subsequently utilized in fermentation processes and efficiently transformed into bioactive compounds that can be used in the food and nutraceutical industry for the development of functional foods with scientifically sustained claims. Microalgae are oleaginous microorganisms that are able to grow in heterotrophic cultures supported by VFA as a carbon source and accumulate high amounts of valuable products, such as omega-3 fatty acids and exopolysaccharides. This article reviews the different types of waste streams in concert with their potential to produce VFA, the possible factors that affect the VFA production process and the utilization of the resulting VFA in microalgae fermentation processes. The biology of VFA utilization, the potential products and the downstream processes are discussed in detail.

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“…Although acetate can be efficiently converted into lipids, butyrate uptake by microalgae is much slower and can reduce the microalgae growth when both VFAs are present. This problem can be solved either by increasing the initial microalgae biomass or by increasing the initial acetate:butyrate ratio [11,13].…”

Section: Introductionmentioning

confidence: 99%