Mixed serous and mucinous retroperitoneal cystadenoma: an extremely rare case

Abstract

Mixed serous and mucinous retroperitoneal cyst adenoma is an extremely rare condition as most of the reported cases in the literature are primary retroperitoneal mucinous cystadenomas and primary retroperitoneal serous cystadenomas. They are initially asymptomatic and become symptomatic gradually depending on their size and anatomical extension and location. We report a 49-year-old woman with a history of right-side abdomen pain for a few years. Diagnostic images revealed a large retroperitoneal cystic lesion. A laparoscopic resection was performed without spillage. The patient was discharged without complication postoperatively and no recurrence on follow-up. Surgical excision, either open/or laparoscopic without any spillage, remains the most effective and appropriate treatment for this lesion.

Primary Retroperitoneal Serous Cyst Adenoma: A Case Report and Literature Review

“…Few case reports suggest an association with elevated serum tumor markers like CEA, CA125, CA19-9, and CA15-3. Some reports also suggest a diagnostic value of tumor markers in aspirated cystic fluid, but these are neither sensitive nor specific [1,[5][6][7][8].…”

“…Unlike secondary lesions, primary retroperitoneal cystic lesions are rare because the retroperitoneum generally lacks epithelial cells. As such, the incidence of PRSCs is difficult to estimate [ 1 , 5 ]. However, these patients have ranged in age from 28 to 79 years and are exclusively female based on the reported cases [ 1 , 6 , 7 ].…”

“…The pathogenesis of PRSCs is also not well understood. Different hypotheses have been described in the literature and include remnants of embryonal urogenital apparatus, heterotopic ovarian tissue, and enteric duplication cysts [ 1 , 5 ].…”

Primary retroperitoneal mucinous cystadenoma: A case report with review of literature

“…From a clinicopathological approach, PRMC could be classified intro three subtypes: mucinous cystadenoma (≈36%), mucinous cystic tumor of borderline malignancy (≈13%), and mucinous cystadenocarcinoma (≈51%) [ 2 ]. Mixed serous and mucinous cystadenomas have also been described [ 12 ].…”