Mixed pulmonary blastoma and carcinosarcoma

Abstract

Pulmonary blastomas and carcinosarcomas are uncommon tumours, accounting for less than 1% of all lung neoplasms. Three previously described mixed epithelial and mesenchymal tumours having both adult and embryonal elements were termed 'transitional'. We report a similar case and evaluate the application of the term 'transitional tumour'.

Blastomatous tumor with teratoid features of nasal cavity: Report of a case and review of the literature

“…The lung was reported to be one of the commonest sites for the blastomatous tumors. 2,3 In the case with pulmonary blastoma and carcinosarcoma reported by Olenick et al, 2 invasive squamous cell carcinoma around immature neuroepithelial nests and the presence of a mesenchymal component with cellular-pleomorphic, spindle cells in storiform pattern were demonstrated.…”

“…These tumors are often seen in the nasal cavity, paranasal sinuses, nasopharynx, lung and base of the skull. [1][2][3][4][5][6][7][8][9][10][11] The term malignant teratoma is used when the tumor is composed of mature squamous epithelial nests, mucous glands, fibroblastic stroma, cartilage, striated muscle tissue and immature neuroepithelial cells with blastomatous structures. 3 Carcinosarcoma is a malignant neoplasm composed of an epithelial and a mesenchymal component.…”

Pleuropulmonary blastoma

“…PB is a tumor of adult life, so named because of its supposed resemblance to stages in fetal lung development. It has been considered by many workers to represent a form of carcinosarcoma [8]. It contains epithelial tubular structures in an immature mesenchymal stroma.…”

Biphasic Tumors of the Lung

“…Some unusual cases show squamous cell carcinoma, and others display transition from blastic to more differentiated areas. 18,30 Histochemical Features…”