Abstract:The combination therapy based on nanoscale materials
has been proven
an effective approach for cancer treatment. In this study, berberine
(BBR) and curcumin (CUR) were loaded into mixed liposomes (CUR-GL/BBR-HL).
To simulate a tumor microenvironment (TME), the dual-cell research
model (SMMC7721 + LX-2) and orthotopic tumor-bearing mice model were
established for antiproliferation and antimetastasis evaluation. The
results showed that the mixed liposomes exhibited strong cytotoxicity
and antimigration effect ag… Show more
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