Mixed exposure to As, Mn, and Pb and dopamine neurotransmission in the striatum ‎

Lee, Daeun; Kim, Haesoo; Sung, Kyunghwa; Kim, Young‐Hee; Kim, Kisok

doi:10.51847/v4atuftzut

Cited by 3 publications

(3 citation statements)

References 18 publications

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“…Additionally, a study from Saudi Arabia discovered that 117 patients (27%) in a cohort of 420 epilepsy patients had a positive family history of the disorder (Chentouf et al, 2015). Additionally, a casecontrol study in Algeria found that there was a 5.37-fold increased risk of having a first-degree relative with epilepsy (Lee et al, 2021).…”

Section: Resultsmentioning

confidence: 99%

“…An epileptic seizure is a transient clinical sign and symptoms of abnormal, synchronous neuronal discharge reside in the cerebral cortex (Fisher et al, 2017;García, 2021;Lee et al, 2021;Mirghani et al, 2021). Epilepsy is clinically characterized by: two or more unprovoked (or reflex) seizures occurring more than 24 hours apart, or one unprovoked (or reflex) seizure and a probability of further seizures similar to the general recurrence risk (at least 60%) after two unprovoked seizures, occurring over the next ten years, or patient is already diagnosed as having epilepsy syndrome (Beretta et al, 2017).…”

Section: Introductionmentioning

confidence: 99%

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Epidemiology of Epilepsy among Pediatric Patients in Tabuk City

Blewi¹,

Abuhamad²,

Abufara³

et al. 2022

World J Environ Biosci

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Epilepsy is a common disease with serious health consequences. Knowledge regarding the clinical pattern of epilepsy is important for its management and prevention. The study aims to investigate the epidemiology of epilepsy among the children following King Salman Armed Forced Hospital in Tabuk city and to determine the frequency of epilepsy according to age, gender, consanguinity, and comorbidities. This is a retrospective observational study conducted among children, in King Salman Armed Forces Hospital in Tabuk, Saudi Arabia. Data from the patient's medical record was collected following its policy on data confidentiality, security, and safety. The study included 200 participants, 53.5% of them were males and 46.5% were females. 31% reported consanguinity between parents. The age of the first epileptic seizure was less than 1 year in 40.5% of patients, 2 years in 16.5%, 5 years old in 7% of patients, and 7 years old in 6.5% of patients. Epilepsy type was generalized in 81%, focal in 5.5%, and combined in 6%. The etiology of epilepsy was idiopathic in 52.5%, hypoxic-ischemic encephalopathy in 14.5%, mental insufficiency in 10%, GDD in 7.5%, ADHD in 3%, and ASD in 3%. Associated co-morbidities were reported as 4.5% infection, 5.5% genetic disorder, 26% structural disabilities, 4.5% metabolic disorder, 4% cerebral palsy, and 4% developmental delay. In conclusion, epilepsy in Tabuk City affected the young age group and was generalized in the majority, more than half were idiopathic. There is a need for further studies to examine the risk factors in greater detail.

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Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Epidemiology of Epilepsy among Pediatric Patients in Tabuk City

Blewi¹,

Abuhamad²,

Abufara³

et al. 2022

World J Environ Biosci

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“…Disorders of the cauda equina are etiologically and physically connected to the neuromuscular system in the spinal cord. A thorough history and neurological examination are necessary for clinical recognition of a cauda equinaaffecting condition, and to make a rapid diagnosis, the selection and interpretation of relevant neuroimaging investigations, neurophysiologic testing, and laboratory tests are necessary [1][2][3][4]. Cauda Equina Syndrome (CES) is hard to identify and treat illness.…”

Section: Introductionmentioning

confidence: 99%

Review on Diagnosis and Management of Cauda Equina

Mohamed¹,

Qahtani²,

Hakeem³

et al. 2023

Int J Pharm Res Allied Sci

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Disorders of the cauda equina are etiologically and physically connected to the neuromuscular system in the spinal cord. A thorough history and neurological examination are necessary for clinical recognition of a cauda equina-affecting condition, and to make a rapid diagnosis, the selection and interpretation of relevant neuroimaging investigations, neurophysiologic testing, and laboratory tests are necessary. The diagnosis and treatment of Cauda Equina Syndrome (CES) are difficult. It could appear at any time or in any environment. It is most common between the ages of 31 and 50. Intervertebral disk herniation was the most frequent cause of conus medullaris and cauda equina lesions, followed by spinal fracture. The Medline, Pubmed, Embase, NCBI, and Cochrane databases were searched for studies of patients with non-alcoholic fatty liver disease. Incidence, etiology, and management options were analyzed. Most academic studies concur that CES is a rare ailment among people who suffer from back pain overall. It is obvious that not all patients with back pain will experience CES, hence not every patient has to be warned. Patients who might eventually develop CES should be "safetynetted" with attentive observation.

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