Mittheilungen aus dem chemischen Laboratorium Fresenius zu Wiesbaden

Steroidal Diglycosides From the Starfish Anthenea Sibogae

“…Anthenea sibogae is an echinoderm species belonging to the genus Anthenea, family Oreasteridae, order Valvatidae, and class Asteroidea. The genus of Anthenea has more than 20 species, distributed mainly in the Indian Ocean and Pacific Ocean [1]. Scientific studies on the chemical composition and biological activity of the genus Anthenea are very limited.…”

“…[3]. The1 H-NMR spectra of the side chain revealed the presence of the three secondary methyl groups [δ H 1.11 (H 3 -21), δ C 24.1 (C-21), δ H 0.88 (H 3 -26), δ C 22.9 (C-26), δ H 0.89 (H 3 -27) and δ C 22.8 (C-27)] and a double bond [δ H 5.79 (H-22), δ C 138.1 (C-22), δ H 5.34 (H-23) and δ C 128.8 (C-23)] (Table 1). The ROESY correlations of H 3 -18/H-20 and H-21; H 3 -21/H β -12, H-22 and H-16 and the chemical shifts of H 3 -21 (δ H 1.11) allowed to determine the 20R-configuration [4].…”