Mitroflow pericardial bioprosthesis: Clinical performance to ten years

Mitroflow aortic pericardial bioprosthesis — clinical performance☆☆☆

“…The experience with earlier model of the prosthesis from Vancouver, Montreal, Victoria and Barcelona was reported on 1995, 1998 and 2008 [1,2,7].…”

“…It is this model that was approved for market in the United States in 2007. All publications on the prostheses either documented the clinical performance of the initial model or combined initial and current models [1][2][3][4][5][6][7]. This study was conducted to evaluate the clinical performance of the current model and, particularly, the durability at the mid term.…”

The Italian study on the Mitroflow postoperative results (ISTHMUS): a 20-year, multicentre evaluation of Mitroflow pericardial bioprosthesis☆

“…Initial experience with the Mitroflow model 11 showed unsatisfactory results regarding mechanical failure [4][5][6], whereas several recent experiences with the modified model 12A have shown good results, predominantly in patients older than 70 years of age [7][8][9]. However, besides the reports of Pomar and colleagues in 1995 and 1998 [5,15], no further multicentre analyses involving more than two centres have been published so far.…”

“…Indeed, Mitroflow valve has the bovine pericardium mounted externally to the valve stents, ensuring a large effective orifice area, and exhibiting excellent haemodynamic performance if compared to other commonly used biological valves [2,3]. After initial concerns about premature prosthetic failure related to pericardial abrasion and tear [4][5][6], a new Mitroflow model (model 12A) has been designed with a manufacturing modification at the ring site. Recent clinical series of the new Mitroflow prosthesis have shown no evidence of the previously encountered valve dysfunction and low incidence of valverelated events [7][8][9].…”

Predictors of Survival and Modes of Failure After Mitroflow Aortic Valve Replacement in 1,003 Adults

“…The Mitroflow valve itself is reported to have favorable performance [19][20][21] in patients with a small aortic annulus [22] and appears to have long-term durability in prior reports [20,[22][23][24][25][26].…”