Mitral valved stent implantation☆☆☆

Lutter, Georg; Quaden, René; Iino, Kenji; Hagemann, A; Renner, Jochen; Hümme, T; Cremer, Jochen; Lozonschi, Lucian

doi:10.1016/j.ejcts.2010.02.022

Cited by 26 publications

(8 citation statements)

References 15 publications

(21 reference statements)

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“…To date, transcatheter mitral or tricuspid valve implantation has only shown success in acute and short-term experimental settings (14)(15)(16)(17)(18)(19). The first trans-atrial mitral valve implantation of a double-crowned valved stent and a subsequent observation period of 30 minutes following stent deployment was reported by von Segesser and colleagues in 2005 (14).…”

Section: Discussionmentioning

confidence: 95%

“…Seventeen animals were observed for a period of 60 minutes after implantation of the mitral valved stent (study group A: 60 min observation period) (15,16). Another 13 animals were observed for a period of seven days after implantation (study group B: Seven day observation period) (17,18). Only in vitro tested valved stents with a very low pressure gradient and a regurgitation of less than grade I were used for transcatheter mitral valve implantation in vivo.…”

Section: Catheter-based Delivery Systemmentioning

confidence: 99%

“…During the last two years, we published the results of four experimental series with an observation period ranging from 60 minutes to up to seven days after implantation of a mitral valved stent (15)(16)(17)(18). This study was designed to present the collective results obtained, focusing on the reproducibility of the results and their significance for future development.…”

Section: Introductionmentioning

confidence: 97%

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Mitral valved stent implantation: An overview

Attmann

Pokorny

Lozonschi

et al. 2011

Minimally Invasive Therapy & Allied Technologies

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To date, transcatheter valve implantation is limited to the replacement of pulmonary and aortic valves. The aim of this study was to analyze a valved stent for minimally invasive implantation in the mitral position. A self-expanding mitral valved stent was designed for transapical implantation. Thirty pigs underwent off-pump mitral valved stent implantation with follow-up times of 60 minutes (n = 17) and seven days (n = 13). Transesophageal echocardiography and computed tomography were used to evaluate stent function and positioning. After valved stent deployment, accurate adjustment of the intra-annular position reduced paravalvular leakage in all animals. Accurate positioning was established in all but five animals. The average mean transvalvular gradient across the mitral valve and the left ventricular outflow tract recorded immediately after deployment, six hours and one week were 1.85 ± 0.95 mmHg, 3.45 ± 1.65 mmHg, 4.15 ± 2.3 mmHg and 1.35 ± 1.35 mmHg, 1.45 ± 0.7 mmHg, 1.9 ± 0.65 mmHg, respectively. No valved stent migration, embolization, systolic anterior movement or left ventricular outflow tract obstruction was observed. The mitral valved stent can be deployed in a reproducible manner to achieve reliable stent stability, minimal gradients across the left ventricular outflow tract and adequate stent function in acute and short term experimental settings.

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Section: Discussionmentioning

confidence: 95%

Section: Catheter-based Delivery Systemmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 97%

See 1 more Smart Citation

Mitral valved stent implantation: An overview

Attmann

Pokorny

Lozonschi

et al. 2011

Minimally Invasive Therapy & Allied Technologies

Self Cite

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show abstract

“…[32][33][34][35][36][37][38][39] During first studies, 30 pigs underwent off-pump mitral valved stent implantation with followup times of 60 minutes and 7 days. Accurate positioning was established in all but 5 animals.…”

Section: Preclinical Developmentmentioning

confidence: 99%

Percutaneous Transcatheter Mitral Valve Replacement

Backer

Piazza

Banai

et al. 2014

Circ: Cardiovascular Interventions

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143

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“…In addition to this unparalleled success in the development of EJCTS [2][3][4][5][6][7][8][9][10], Ludwig von Segesser launched a second publication in September 2002, Interactive CardioVascular and Thoracic Surgery (ICVTS). This interactive Journal is available to the reader in both a printed and an online version.…”

mentioning

confidence: 99%