Mitral valve prolapse in anxiety neurosis (panic disorder)

Prevalence of Mitral Valve Prolapse in Saudi Sickle Cell Disease Patients in Dammam — A Prospective-Controlled Echocardiographic Study

“…17 There was also no significant difference in BSA of the two groups of patients studied by Lippman et al 11 The ease of diagnosis of MVP by echocardiography and the wave of interest that followed its initial description resulted in numerous case reports and small clinical studies claiming association of MVP with a wide variety of conditions. [6][7][8][9][10][11][12][13][14][15][16] A good example is Marfan syndrome, which has been variously reported to be associated with MVP. 6,7 This is a rare condition occurring in one per 10,000 population.…”

“…3 A wide range of conditions have been reported to be associated with MVP. [6][7][8][9][10][11][12][13][14][15][16] Many of these conditions are in themselves rare and the reports are based mostly on case reports and small clinical studies. 3 With an MVP prevalence of 2.5% to 5% in the general population, 3,17 many of these reported associations appear weak.…”

Does the Association Between Mitral Valve Prolapse and Panic Disorder Really Exist?

“…7 A control group of "normal" subjects was included in 11 studies (Table 2), with an important division occurring in these studies. In 7 of them, the control group consisted of hospital employees 13,47,50,64 or volunteers from the community, 49,59,61 a fact that can be considered another important selection bias. In 4 of these studies, a higher prevalence of MVP was detected in the case group.…”

“…In 4 of these studies, a higher prevalence of MVP was detected in the case group. 13,47,49,50 The other group of articles consisted of 4 studies in which the control group was formed by outpatients who were being followed due to complaints other than panic disorder/panic Abbreviations: 2D echo = 2-dimensional echocardiography, Ausc = auscultation, GAD = generalized anxiety disorder, MDD = major depressive disorder, MVP = mitral valve prolapse.…”

Changes in the Drug Treatment of Anxiety Disorders

“…One candidate for an overlapping illness is mitral valve prolapse since panic disorders may be associated with it [27][28][29], Even if mitral valve prolapse is responsible, how ever, the majority of panic disorder patients do not have the condition. Therefore, mitral valve prolapse does not explain all panic dis orders.…”