“…At the first glance, the susceptibility to H7N9 infection and the susceptibility to severe H1N1 infection are not equivalent issues. In fact, H7N9 infection and severe H1N1 infection essentially shared the same pathology, i.e., viral pneumonia, the most lethal consequence of influenza (Nikolaidis et al , ). Overall, pandemic H1N1 viruses exhibit binding specificity to human‐type α2,6‐linked sialic acid receptor (Zhou et al , ); the viruses tend to replicate more actively in human bronchus than in lung tissue (Chan et al , ).…”