Mitogen-Induced Activation of Stable E-Rosettes by Human Lymphocytes

Abstract

Following on an earlier study which demonstrated that PHA can activate human lymphocytes to form temperature-stable (37 degrees C.) E-rosettes with sheep red blood cells, a number of other mitogens were tested. These included Concanavalin A, pokeweed mitogen, soybean agglutinin, sodium periodate, and galactose oxidase. All except soybean agglutinin demonstrated the capability to activate lymphocytes to form stable E-rosettes.