Mitochondrion-targeted two-photon probes: Real-time monitoring endogenous GSH via situ reaction in Hela cells

Novel Rhodamine-Derivated Dual-Responsive Colorimetric Fluorescent Chemoprobe for the Hypersensitive Detection of Ga3+ and Hg2+ and Biological Imaging

“…Actually, there are a variety of abundant mercapto biomolecules in organisms, like the common biothiols (e.g., glutathione, cysteine, and homocysteine), which can easily interact with Hg 2+ . In general, the sensing mechanism and luminescence features play a definitive role in the biological application of the metal cation fluorescent chemoprobe.…”

Emerging advances in fluorescence imaging and phototherapy of arthritis

“…In addition, the high brightness and signal-to-noise ratio of two-photon microscopy make it suitable for prolonged observation of living cells and tissues, as well as for in-depth study of thick biological samples. [73][74][75] In addition to the enhancement of FL technology, the development of fluorescent dyes has contributed significantly to the development of FL imaging, including molecules with aggregation-induced emission (AIE) [76,77] and the synthesis of novel near-infrared (NIR) molecules. [78] The traditional FL imaging modality of the NIR first window (NIR-I, 400-900 nm) is more damaging to tissues due to the shorter wavelength and higher FL energy, and the limited penetration depth of short-wavelength FL, high injection dose, and in vivo tissue autofluorescence mostly in the first NIR window, which also makes the resolution of FL imaging limited and less suitable for bioimaging.…”

“…In addition, the high brightness and signal‐to‐noise ratio of two‐photon microscopy make it suitable for prolonged observation of living cells and tissues, as well as for in‐depth study of thick biological samples. [ 73–75 ]…”