Mitochondrial polymorphisms associated with differential longevity do not impact lifetime‐reproductive success

Abstract

Although LAPS significantly affect longevity, such differential longevity does not result in differential lifetime reproductive success. From an evolutionary perspective, these longevity-associated polymorphisms do not affect the carriers' Darwinian fitness.

Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population

“…Furthermore, understanding admixture in this population is essential for disease susceptibility mapping studies, and Costa Rica's population has been extensively studied for psychiatric diseases (Contreras et al 2010;Escamilla et al 2009;Escamilla et al 2007; Walss- Bass et al 2006;Walss-Bass et al 2009), longevity (Castri et al 2011;Castri et al 2009) and other disease studies (Leon et al 1992). …”

Ancestry Informative Markers Clarify the Regional Admixture Variation in the Costa Rican Population

“…Furthermore, understanding admixture in this population is essential for disease susceptibility mapping studies, and Costa Rica's population has been extensively studied for psychiatric diseases (Contreras et al 2010;Escamilla et al 2009;Escamilla et al 2007;Walss-Bass et al 2006;Walss-Bass et al 2009), longevity (Castri et al 2011;Castri et al 2009) and other disease studies (Leon et al 1992).…”