Mitochondrial monoamine oxidase activity during preneural developmental stages of Bufo bufo

Senatori, Ornella; Nicotra, Antonietta

doi:10.1016/0742-8413(85)90013-1

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1989

1990

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Cited by 2 publications

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“…In a previous paper (11) we have demonstrated that the P. lividus egg displays a monoamine oxidase activity classified as MA0 B form. A significant level of MA0 activity has been demonstrated recently in our laboratory also in toad eggs and early embryos (14,17). Both in sea urchin and amphibian early embryos a monoaminergic system might be involved in the regulation of cell division (1,16,18).…”

Section: Discussionmentioning

confidence: 80%

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Deprenyl, an Inhibitor of Monoamine Oxidase B, Delays the First Two Mitotic Cycles of Sea Urchin eggs

Nicotra¹,

Serafino²,

Arizzi³

1989

Dev Growth Differ

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Sea urchin eggs are known to display a significant level of monoamine oxidase B activity. Deprenyl, a highly selective inhibitor of monoamine oxidase B, was found to prolong the length of the first two mitotic cycles of the sea urchin egg. The prophase seems to be specifically prolonged by the drug, while the length of the other phases of the cycle is unaffected. These results suggest that the monoamine oxidase B may be a component of the monoaminergic system acting during the divisions of the sea urchin eggs.

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Section: Discussionmentioning

confidence: 80%

“…A significant level of MA0 activity has been demonstrated recently in our laboratory also in toad eggs and early embryos (14,17). Both in sea urchin and amphibian early embryos a monoaminergic system might be involved in the regulation of cell division (1,16,18).…”

Section: Discussionmentioning

confidence: 95%