Mitochondrial carrier homolog 2 increases malignant phenotype of human gastric epithelial cells and promotes proliferation, invasion, and migration of gastric cancer cells
Jing-Wen Zhang,
Ling-Yan Huang,
Ya-Ning Li
et al.
Abstract:BACKGROUND
The precise role of mitochondrial carrier homolog 2 (MTCH2) in promoting malignancy in gastric mucosal cells and its involvement in gastric cancer cell metastasis have not been fully elucidated.
AIM
To determine the role of MTCH2 in gastric cancer.
METHODS
We collected 65 samples of poorly differentiated gastric cancer tissue and adjacent tissues, constructed MTCH2-overexpressing and MTCH2-knockdown cell models, and evaluated the proliferation, migra… Show more
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