Mitochondria in depression: The dysfunction of mitochondrial energy metabolism and quality control systems
Mengruo Jiang,
Liyuan Wang,
Hui Sheng
Abstract:BackgroundDepression is the most disabling neuropsychiatric disorder, causing difficulties in daily life activities and social interactions. The exact mechanisms of depression remain largely unclear. However, some studies have shown that mitochondrial dysfunction would play a crucial role in the occurrence and development of depression.AimsTo summarize the known knowledge about the role of mitochondrial dysfunction in the pathogenesis of depression.MethodsWe review the recent literature, including 105 articles… Show more
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