Mitigation of Genotoxic and Cytotoxic Effects of Silver Nanoparticles on Onion Root Tips using some Antioxidant Scavengers

Hafez, Rehab M.; Fouad, Ahmed S.

doi:10.21608/ejbo.2019.13390.1321

Cited by 15 publications

(14 citation statements)

References 43 publications

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“…A similar study reported that the DPPH scavenging ability of the foxtail millet increased from 35.44 to 63.07mM trolox/g at the time of germination may be due to increased concentration of hexadecanoic acid methyl ester; 9,12-Octadecadienoic acid ethyl ester and synthesis of new polyphenolic compounds like pentadecanoic acid; 14-methyl methyl ester; 9,12,15Octadecatrienoic acid.During germination some bound components might have liberated and played a role in DPPH and hydrogen peroxide scavenging when the endosperm has modified by the hydrolytic enzymes [21]. Similar results are in accordance with [22].…”

Section: Changes In Levels Of Enzymic Antioxidantsupporting

confidence: 80%

Impact of soaking, sprouting on antioxidant and anti-nutritional factors in millet grains

Bhuvaneshwari

Nirmalakumari

Senthil

2020

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Commonly consumed millet types viz., Little millet, foxtail millet, pearl millet, finger millet, and Kodo millet were tested under two processing methods of soaking and germination at a different time point. Most popular processing practices adopted by Indian households were studied for their influence on the biochemical properties, antioxidant profile, and anti-nutritive factors. The results showed that the sprouting process showed a maximum influence on the antioxidant and anti-nutritive factors. The comparative analysis of the five millets suggested 24h soaking and 24h germination was found to be best for producing nutritionally enriched millet products. Tannin content decreases with an increase in germination. The reduction in tannin was about 50% in little millet (0.347 mg/g) and the highest was recorded in finger millet (2.07 mg/g). The highest amount of saponin content was found in pearl millet( 39.53 mg/g) followed by finger millet ( 34.86 mg/g) with 24 hr soaking and 24 hr germination. The phytase activity was found to be higher in little millet (61.520 u/kg) when prolonged soaking and germination. The DPPH assay showed sprouted foxtail millet grains contain more antioxidant activity (81.13%) when extent the period of soaking and germination.

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Section: Changes In Levels Of Enzymic Antioxidantsupporting

confidence: 80%

Impact of soaking, sprouting on antioxidant and anti-nutritional factors in millet grains

Bhuvaneshwari

Nirmalakumari

Senthil

2020

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“…Nevertheless, multiple studies have demonstrated that uncoated or differently coated AgNPs have induced oxidative damage while inducing aneugenic or clastogenic effects. Regarding the clastogenic effects, it was reported that uncoated as well as citrate- and PVP-coated AgNPs induced DNA breaks in V. faba [ 82 ], tobacco [ 61 , 156 ], and A. cepa [ 65 , 135 , 158 , 159 ], respectively, while uncoated and PVP-coated ones further induced chromosomal aberrations and increased levels of micronucleus [ 82 , 159 ]. Moreover, concerning the aneugenic outcomes, exposure to uncoated AgNPs as well as to those coated with either citrate or PVP has led to a significant decrease in mitotic index in V. faba [ 82 ] and A. cepa [ 65 , 158 , 159 ].…”

Section: Oxidative Stress Induction and Mobilization Of Antioxidant Machinerymentioning

confidence: 99%

“…Regarding the clastogenic effects, it was reported that uncoated as well as citrate- and PVP-coated AgNPs induced DNA breaks in V. faba [ 82 ], tobacco [ 61 , 156 ], and A. cepa [ 65 , 135 , 158 , 159 ], respectively, while uncoated and PVP-coated ones further induced chromosomal aberrations and increased levels of micronucleus [ 82 , 159 ]. Moreover, concerning the aneugenic outcomes, exposure to uncoated AgNPs as well as to those coated with either citrate or PVP has led to a significant decrease in mitotic index in V. faba [ 82 ] and A. cepa [ 65 , 158 , 159 ]. However, no genotoxic effects were found upon exposure of A. cepa roots to AgNPs coated with PVP [ 160 ] or chitosan [ 161 ], as well as after exposing tobacco plants to AgNP-citrate [ 47 ].…”

Section: Oxidative Stress Induction and Mobilization Of Antioxidant Machinerymentioning

confidence: 99%

Surface Coating-Modulated Phytotoxic Responses of Silver Nanoparticles in Plants and Freshwater Green Algae

et al. 2021

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Silver nanoparticles (AgNPs) have been implemented in a wide range of commercial products, resulting in their unregulated release into aquatic as well as terrestrial systems. This raises concerns over their impending environmental effects. Once released into the environment, they are prone to various transformation processes that modify their reactivity. In order to increase AgNP stability, different stabilizing coatings are applied during their synthesis. However, coating agents determine particle size and shape and influence their solubility, reactivity, and overall stability as well as their behavior and transformations in the biological medium. In this review, we attempt to give an overview on how the employment of different stabilizing coatings can modulate AgNP-induced phytotoxicity with respect to growth, physiology, and gene and protein expression in terrestrial and aquatic plants and freshwater algae.

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“…H 2 O 2 and other ROS generated during oxidative stress is associated with damage to cellular macromolecules, including DNA [57,58] and chlorophyll [59,60]. The injurious impact of H 2 O 2 on DNA supports its utilization as a positive control in plant comet assays [61].…”

Section: Discussionmentioning

confidence: 99%

Boosting Polyamines to Enhance Shoot Regeneration in Potato (Solanum tuberosum L.) Using AgNO3

et al. 2022

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Advancements in shoot regeneration systems support biotechnology-based tools used in the genetic improvement of plant crops. This study aims to enhance shoot regeneration in potatoes by boosting polyamine content by adding AgNO3 to the shoot regeneration medium (MS medium supplemented with 30 g L−1 sucrose, 100 mg L−1 myoinositol, and 2.25 BA mg L−1). Five concentrations of AgNO3 (2, 4, 6, 8, and 10 mg L−1) were used in addition to a control. The effect of AgNO3 on regeneration assumed a more or less concentration-dependent bell-shaped curve peaking at 4 mg L−1. Enhancements in shoot regeneration were attributed to the known role of AgNO3 as an ethylene action blocker in addition to improvements in polyamine accumulation without an increase in H2O2 content, lipid peroxidation, or DNA damage. The uncoupling of shoot regeneration and polyamine content recorded at high AgNO3 concentrations can be attributed to the consumption of polyamines to counteract the synchronized oxidative stress manifested by increases in H2O2 content, lipid peroxidation, and DNA damage.

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Mitigation of Genotoxic and Cytotoxic Effects of Silver Nanoparticles on Onion Root Tips using some Antioxidant Scavengers

Cited by 15 publications

References 43 publications

Impact of soaking, sprouting on antioxidant and anti-nutritional factors in millet grains

Impact of soaking, sprouting on antioxidant and anti-nutritional factors in millet grains

Surface Coating-Modulated Phytotoxic Responses of Silver Nanoparticles in Plants and Freshwater Green Algae

Boosting Polyamines to Enhance Shoot Regeneration in Potato (Solanum tuberosum L.) Using AgNO3

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