Mitigation and use of biofilms in space for the benefit of human space exploration

Justiniano, Yo-Ann Velez; Goeres, Darla M.; Sandvik, Elizabeth L.; Kjellerup, Birthe V.; Sysoeva, Tatyana A.; Harris, Jacob S.; Warnat, Stephan; McGlennen, Matthew; Foreman, Christine M.; Yang, Jiseon; Li, Wenyan; Cassilly, Chelsi D.; Lott, Katelynn; HerrNeckar, Lauren E.

doi:10.1016/j.bioflm.2022.100102

Cited by 6 publications

(6 citation statements)

References 117 publications

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“…An important advantage of these microorganism based-processes involving biofilms is that they could be adapted to recycle organic matter from waste. More generally, biofilms are envisioned in various in-situ resource utilization (ISRU) procedures in space travel such as biomining or bioregenerative life-support systems [260]. extreme environmental stress tolerance.…”

Section: Discussionmentioning

confidence: 99%

Migration of surface-associated microbial communities in spaceflight habitats

Marra

Karapantsios

Caserta

et al. 2023

Biofilm

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Section: Discussionmentioning

confidence: 99%

Migration of surface-associated microbial communities in spaceflight habitats

Marra

Karapantsios

Caserta

et al. 2023

Biofilm

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“…Larger particles which would settle out on Earth also harbor higher concentrations of microbes ( Haines et al, 2019 ). Furthermore, there is research pointing towards alterations of virulence of pathogens in microgravity ( Velez Justiniano et al, 2023 ).…”

Section: Environmental Hazards Associated With Space Travelmentioning

confidence: 99%

Dry eye disease in astronauts: a narrative review

Ax,

Ganse,

Fries

et al. 2023

Front. Physiol.

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Long-duration spaceflight can have adverse effects on human health. One of the most common ocular conditions experienced by astronauts is dry eye disease (DED). Symptoms of DED include feelings of eye irritation, eye strain, foreign body sensation and blurred vision. Over 30% of International Space Station expedition crew members reported irritation and foreign body sensation. We reviewed the current literature on the prevalence and mechanisms of DED in astronauts and its potential implications for long-duration spaceflight, including the influence of environmental factors, such as microgravity and fluid shift on tear film physiology in space. DED has negative effects on astronaut performance, which is why there is a need for further research into the pathophysiology and countermeasures. As an in-flight countermeasure, neurostimulation seems to be among the most promising options.

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“…Taking also into account the exposure to microgravity, microbial biofilms can display unpredicted behavior related to increased virulence and antimicrobial resistance (Yang et al, 2021). It is perfectly understood that for any extended space mission, including the upcoming travel to the Moon and Mars (Vélez Justiniano et al, 2023), uncontaminated water is really essential. Therefore, it is pivotal to diminish the microbiological threats that could possibly risk the crew's health and mission success.…”

Section: Introductionmentioning

confidence: 99%

Effect of surface treatment and shear flow on biofilm formation over materials employed in space water storage and distribution systems

Avgoulas,

Petala,

Briandet

et al. 2024

Front. Mater.

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The prolonged duration of future manned space missions conceals potential threats associated with microbial contamination. Such closed environments are susceptible to formation of complex biofilm communities, where microorganisms can thrive and further evolve. The objective of this study was to evaluate the impact of surface type, surface treatment and shear stress on biofilm formation in water facilities. To that aim, the ability of Pseudomonas fluorescens SBW25 to adhere on three space applications related materials, including passivated (SS) and both passivated and electropolished (SSEP) stainless steel, as well as Ti-6Al-4V (Ti) alloy was studied under stagnant and shear stress conditions after 24 h of exposure. Results indicated that surface type strongly affects bacterial adhesion under the same conditions. Surface coverage during static experiments was in the following order: SS > Ti > SSEP, while SS exhibited a fourfold surface coverage compared to SSEP highlighting the significance of surface treatment. Moreover, SS and Ti stimulate the formation of several microcolonies and their growth. On the other hand, the application of shear stress diminished bacterial attachment to the studied materials, the degree of which relied on the material type. In this case, bacterial settlement on SS and Ti was dependent on the surface texture, implying that surface roughness may also play an important role in cell adhesion under shear conditions. Furthermore, the metallic surfaces did not hinder bacterial attachment when silver ions were previously deposited on their surface. The deposition that occurs on metallic surfaces when in contact with water disinfected with silver ions, for example, during space missions, highlights its impact on the loss of disinfection capacity of silver ions.

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Mitigation and use of biofilms in space for the benefit of human space exploration

Cited by 6 publications

References 117 publications

Migration of surface-associated microbial communities in spaceflight habitats

Migration of surface-associated microbial communities in spaceflight habitats

Dry eye disease in astronauts: a narrative review

Effect of surface treatment and shear flow on biofilm formation over materials employed in space water storage and distribution systems

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