Mitigating Vaccine Hesitancy and Building Trust to Prevent Future Measles Outbreaks in England

Thompson, Sarah L.; Meyer, Johanna C.; Burnett, Rosemary J.; Campbell, Stephen

doi:10.3390/vaccines11020288

Cited by 19 publications

(16 citation statements)

References 84 publications

(146 reference statements)

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“…Strategies must encompass transparent communication, targeted education campaigns, and building trust with communities. These efforts aim to combat misinformation, allay safety concerns, and address historical mistrust, ultimately working towards achieving widespread immunity and bringing an end to the COVID-19 pandemic [37,38].…”

Section: Discussionmentioning

confidence: 99%

Psychosocial Factors Influencing Vaccine Hesitancy: A Study in the Context of COVID-19

Rahel

2024

Preprint

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The COVID-19 pandemic has underscored the critical need to comprehend vaccine hesitancy, a multifaceted issue with substantial repercussions for the success of vaccination campaigns. This study delves into vaccine hesitancy within a cohort of 560 individuals. Within this group, 157 individuals (28%) opted to receive the Pfizer vaccine, while the remaining 403 (72%) expressed hesitancy towards vaccination. Hesitant individuals were further classified into five distinct categories: 210 harbored concerns about potential vaccine side effects, 172 were influenced by misinformation and disinformation, and 21 exhibited a historical mistrust of vaccines. Notably, our survey did not unearth any instances of vaccine hesitancy stemming from political polarization or access barriers. Furthermore, we conducted a comprehensive analysis of biological markers in the 157 vaccinated individuals to evaluate vaccine side effects. This analysis unveiled significant variations in blood test parameters, such as D-Dimer, CRP, and WBC levels, between the first week and three weeks following vaccination (p < 0.0001 and p = 0.001, respectively). To sum it up, our results indicate that the vaccination process is a standard and medically valid procedure. Nevertheless, several factors play a role in individuals' vaccine hesitancy. It is imperative for both the government and healthcare systems to provide accurate information to the public about the significance of vaccination. Recognizing and tackling these factors are essential for successful vaccination initiatives and, in the end, attaining widespread immunity.

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Section: Discussionmentioning

confidence: 99%

Psychosocial Factors Influencing Vaccine Hesitancy: A Study in the Context of COVID-19

Rahel

2024

Preprint

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“…A second-dose MMR vaccine program began in 1996, which was given as a preschool booster vaccination to maintain infection control and as an attempt to eliminate measles [ 10 ]. National campaigns in the UK were introduced to target specific age groups and social groups where vaccine coverage was identified as low [ 38 , 39 ]. Successful herd immunity was achieved for measles in the UK by 2017, reaching the WHO 95% coverage target for the first MMR dose, resulting in the UK’s measles elimination status [ 38 , 39 ].…”

Section: Measles In the United Kingdom (Uk)mentioning

confidence: 99%

“…National campaigns in the UK were introduced to target specific age groups and social groups where vaccine coverage was identified as low [ 38 , 39 ]. Successful herd immunity was achieved for measles in the UK by 2017, reaching the WHO 95% coverage target for the first MMR dose, resulting in the UK’s measles elimination status [ 38 , 39 ]. Measles elimination is defined as the absence of endemic measles transmission within a defined geographical area for at least 12 months [ 6 ].…”

Section: Measles In the United Kingdom (Uk)mentioning

confidence: 99%

A Review of the Resurgence of Measles, a Vaccine-Preventable Disease, as Current Concerns Contrast with Past Hopes for Measles Elimination

Parums

2024

Med Sci Monit

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On 22 February 2024, the World Health Organization (WHO) stated that, following the recent resurgence of measles cases in Europe, more than half the world’s countries could expect significant measles outbreaks this year. Measles is a highly infectious virus with a primary case reproduction number (R0) of 12–18. Measles infection can be severe, resulting in pneumonia, and also more rarely in subacute sclerosing panencephalitis (SSPE), which occurs in 1 child out of every 1,000 and can be fatal. Until the 1990s, the hope of eliminating measles seemed possible following the successful development of effective vaccines, given individually or in the combined measles, mumps, and rubella (MMR) vaccine. Vaccine hesitancy due to misinformation about possible vaccine side effects, reduced vaccine uptake during and after the COVID-19 pandemic, and lack of awareness of the severe consequences of measles infection have contributed to low vaccine uptake, resulting in vulnerable communities. This article aims to review the recent resurgence of measles cases in the US, Europe, and the UK, to provide a reminder of the potential severity of measles, and to consider the causes of the failure to eliminate this vaccine-preventable viral infection.

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“…22 This model has been found to be applicable to various populations and vaccine products. [23][24][25][26][27] Below, we apply it to the unique considerations for RSV vaccination in the older adult population.…”

Section: Knowledge Into Practicementioning

confidence: 99%

RSV vaccination in older adults: Addressing vaccine hesitancy using the 3C model

Houle,

Andrew

2023

Can Pharm J

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The first vaccine against respiratory syncytial virus (RSV) targeting older adults was approved for use in Canada in August 2023. As a frequent first point of contact for Canadians seeking advice on vaccination and the most common setting for the administration of influenza vaccines, community pharmacies will also play a role in RSV vaccination efforts. To address vaccine hesitancy confidently and effectively, pharmacists must be equipped with knowledge of the factors that affect a person’s decision on whether to be vaccinated or not. The 3C Model of Vaccine Hesitancy summarizes these as complacency, confidence and convenience. This article introduces the model and describes the often-underrecognized relevance of RSV to older adults, including risk factors and burden of disease. It also reviews the history and status of vaccine development and approval and presents clinical trial data to equip pharmacists to discuss RSV vaccination with older adults who express vaccine hesitancy.

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Mitigating Vaccine Hesitancy and Building Trust to Prevent Future Measles Outbreaks in England

Cited by 19 publications

References 84 publications

Psychosocial Factors Influencing Vaccine Hesitancy: A Study in the Context of COVID-19

Psychosocial Factors Influencing Vaccine Hesitancy: A Study in the Context of COVID-19

A Review of the Resurgence of Measles, a Vaccine-Preventable Disease, as Current Concerns Contrast with Past Hopes for Measles Elimination

RSV vaccination in older adults: Addressing vaccine hesitancy using the 3C model

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