Intelligent vehicle technologies are opening new possibilities for decentralized vehicle routing systems, suitable for regulating large traffic networks, and at the same time, capable of providing customized advice to individual vehicles. In this study, we perform a rigorous simulation-based analysis of an in-vehicle routing strategy that aims to achieve a user-equilibrium distribution in traffic. Novel features of the approach include: a mechanism based on forward propagation of individual vehicle decisions to anticipate future traffic dynamics; time-dependent prediction of route travel times with neural network-based link predictors; and a stochastic routing policy for invehicle decision-making based on predicted travel times. However, for an effective application of the approach, design choices need to be made regarding the accuracy of the link predictors, and some control settings. These choices may depend on the network size and structure. We investigate the impact of two important design aspects: sequentially using link-level predictors for route travel time estimation, and the control parameter values, on the equilibrium performance at the networklevel. The results suggest functional scalability of the approach, in terms of the prediction model accuracy and routing performance. Overall, the work contributes to a qualitative and quantitative understanding of emergent performance from the given routing approach. 1. Introduction Dynamic route guidance in freeway or urban traffic networks with time-varying demand and stochastic travel times is a classic transportation problem (Papageorgiou, 1990). At the same time, recent advances in automated and connected vehicle capabilities (Shladover, 2017), boosted by other emerging technologies, like cloud computing, artificial intelligence, big data, and internet of things, are fundamentally transforming the potential and design of traffic control systems (Diakaki et al., 2015; Papageorgiou et al., 2015). In-vehicle route guidance systems, be they satellite navigation devices or GPS enabled smartphone applications, such as Google Maps, Waze, and Apple Maps, are becoming ubiquitous and connected. These trends are making decentralized routing approaches increasingly more practicable. The benefits of a decentralized control structure range from lower computation and communication loads, higher fault tolerance, to robustness against measurement errors, delays and failures. Moreover, decentralized decision-making makes it possible to provide personalized advice to individual vehicles. We focus on decentralized route guidance systems that can achieve a user-equilibrium (UE) condition, famously known as the Wardrop's first principle of route choice