Missing T-cell receptor Vβ families following blood transfusion

Munson, Jennifer L.; Twuyver, E. van; Mooijaart, R. J. D.; Roux, Étienne; Berge, Ineke J. M. ten; Waal, L. P. de

doi:10.1016/0198-8859(94)00055-u

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Cited by 22 publications

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“…In this respect, we have found another intruiging effect of blood transfusion on the T cell repertoire. HLA-sharing blood transfusion not only leads to functional holes in the CTL response but also induces a selective decrease in the usage of T cell receptor VB families [14], Thus, HLA-sharing blood transfusion affects the T cell repertoire in a specific and non-specific fashion. How can we explain the immunomodulating effects of blood transfusion?…”

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confidence: 99%