Misdiagnosis in Amyotrophic Lateral Sclerosis

Thomson, Cameron G.; Hutchinson, Peter J.; Stern, Peter J.

doi:10.1016/j.jhsa.2023.03.023

Cited by 3 publications

(2 citation statements)

References 30 publications

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“…The results of this case study demonstrate how withholding or deleting medical history information can result in incorrect diagnoses in clinical settings. [16][17][18][19][20]…”

Section: Discussionmentioning

confidence: 99%

Misdiagnosis Diagnosis of Pneumocystis Pneumonia as Chemical Pneumonitis

Zhou,

Jiang,

Kong

et al. 2024

IDR

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Background: Auxiliaries, a mixed chemicals, for printing and dyeing characterized by their diverse range and complex chemical compositions are commonly utilized in the textile industry. These chemicals can lead to environmental contamination and pose health risks to humans. Case Description: A 29-year-old man who worked in a printing and dyeing factory in Suzhou, China, reported having tightness in his chest and coughing. Despite seeking medical treatment at several hospitals, the initial diagnosis remained elusive. High-resolution chest CT scans showed multifocal lesions in both lungs. The patient had no significant medical history, and the respiratory symptoms only surfaced after exposure to dyeing auxiliaries. Physicians initially suspected chemical pneumonitis due to occupational exposure. However, a subsequent evaluation at a hospital specializing in occupational diseases led to a diagnosis of AIDS and pneumocystis pneumonia. Conclusion:This case underscores the importance of comprehensive clinical diagnosis to avoid biases and reduce the incidence of misdiagnosis.

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“…The results of this case study demonstrate how withholding or deleting medical history information can result in incorrect diagnoses in clinical settings. [16][17][18][19][20]…”

Section: Discussionmentioning

confidence: 99%

Misdiagnosis Diagnosis of Pneumocystis Pneumonia as Chemical Pneumonitis

Zhou,

Jiang,

Kong

et al. 2024

IDR

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“…Signs of axonal degeneration and metabolic conduction block, compared to normal findings or only an impaired nerve conduction velocity, could indicate a poorer outcome of the surgical treatment [ 23 ]. If other neuropathy, including motor neuron disease, is suspected, a meticulous clinical examination as well as an electrophysiological examination with electromyography should be performed [ 103 ]. Depending on what the surgeon suspects is the cause of the symptoms, a conventional X-ray of the elbow, wrist, and cervical spine, as well as an X-ray of the lungs, can be carried out [ 104 ].…”

Section: Ulnar Nerve Entrapmentmentioning

confidence: 99%

The Unpredictable Ulnar Nerve—Ulnar Nerve Entrapment from Anatomical, Pathophysiological, and Biopsychosocial Aspects

Nyman,

Dahlin

2024

Diagnostics

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Peripheral nerves consist of delicate structures, including a rich microvascular system, that protect and nourish axons and associated Schwann cells. Nerves are sensitive to internal and external trauma, such as compression and stretching. Ulnar nerve entrapment, the second most prevalent nerve entrapment disorder after carpal tunnel syndrome, appears frequently at the elbow. Although often idiopathic, known risk factors, including obesity, smoking, diabetes, and vibration exposure, occur. It exists in all adult ages (mean age 40–50 years), but seldom affects individuals in their adolescence or younger. The patient population is heterogeneous with great co-morbidity, including other nerve entrapment disorders. Typical early symptoms are paresthesia and numbness in the ulnar fingers, followed by decreased sensory function and muscle weakness. Pre- and postoperative neuropathic pain is relatively common, independent of other symptom severity, with a risk for serious consequences. A multimodal treatment strategy is necessary. Mild to moderate symptoms are usually treated conservatively, while surgery is an option when conservative treatment fails or in severe cases. The decision to perform surgery might be difficult, and the outcome is unpredictable with the risk of complications. There is no consensus on the choice of surgical method, but simple decompression is relatively effective with a lower complication rate than transposition.

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