miRNA profiling of granulosa cell‐derived exosomes reveals their role in promoting follicle development
Qilin Zhou,
Zhen Liu,
Zhengdong Liao
et al.
Abstract:To explore whether granulosa cell (GC)‐derived exosomes (GC‐Exos) and follicular fluid‐derived exosomes (FF‐Exos) have functional similarities in follicle development and to establish relevant experiments to validate whether GC‐Exos could serve as a potential substitute for follicular fluid‐derived exosomes to improve folliculogenesis. GC‐Exos were characterized. MicroRNA (miRNA) profiles of exosomes from human GCs and follicular fluid were analyzed in depth. The signature was associated with folliculogenesis,… Show more
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