“…Therefore, they may be of particular value in defining variance of genomic expression. cffmiRNAs are derived from fragments and microparticles of remodeled trophoblast and are transported into the maternal circulation as microvesicles or nanovesicles, which provide protection from degradation . Differential expression of cffmiRNAs has been described in pregnancies affected by severe intrauterine growth restriction, the presence of a fetal neural tube defect and in fetal trisomies 21 and 13 .…”
“…Therefore, they may be of particular value in defining variance of genomic expression. cffmiRNAs are derived from fragments and microparticles of remodeled trophoblast and are transported into the maternal circulation as microvesicles or nanovesicles, which provide protection from degradation . Differential expression of cffmiRNAs has been described in pregnancies affected by severe intrauterine growth restriction, the presence of a fetal neural tube defect and in fetal trisomies 21 and 13 .…”
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