Quercetin, a naturally occurring polyphenolic compound found in abundance
in vegetables and fruits, has emerged as a compelling subject of study in cancer treatment.
This comprehensive review delves into the significance and originality of quercetin's
multifaceted mechanisms of action, with a particular focus on its application in various
brain tumors such as glioblastoma, glioma, neuroblastoma, astrocytoma, and medulloblastoma.
This review scrutinizes the distinctive facets of quercetin's anti-cancer properties,
highlighting its capacity to modulate intricate signaling pathways, trigger apoptosis,
impede cell migration, and enhance radiosensitivity in brain tumor cells. Significantly,
it synthesizes recent research findings, providing insights into potential structure-activity
relationships that hold promise for developing novel quercetin derivatives with
heightened effectiveness. By unraveling the unique attributes of quercetin's anti-brain tumor
effects and exploring its untapped potential in combination therapies, this review
contributes to a deeper comprehension of quercetin's role as a prospective candidate for
advancing innovative treatments for brain cancer.