“…Members of miRNA-29 family have been known to play an important role in cancer by regulating cell differentiation, proliferation, apoptosis, invasion, and migration. 4,5 However, clinical application of this relatively novel therapeutic faces many challenges, including degradation in serum, rapid blood clearance, stimulation of immune response, off-target effects, and poor cellular uptake. 6 Recently, our group developed a novel targeted hybrid nanoparticle delivery system.…”