Minocycline treatment results in reduced oral steroid requirements and suppresses IgE responses in adult asthma

Adjunctive Probiotics Alleviates Asthmatic Symptoms via Modulating the Gut Microbiome and Serum Metabolome

“…The serum IgE levels were significantly and continuously increased in placebo but not Probio-M8 group during the trial period. It is known that an increased level of IgE could contribute to aggravation of symptoms in patients with bronchial asthma, although several previous clinical studies observed no significant change in the IgE level even with desirable clinical outcomes after probiotic or other intervention ( 32 – 34 ). These discordant findings are suggestive of the existence of multiple disease pathways that could be differentially targeted by different therapeutics or management approaches.…”