Minocycline induced organising pneumonia resolving without recourse to corticosteroids

Branley, Howard M.; Kolvekar, Shyamsunder; Brull, David

doi:10.1016/j.rmedc.2008.12.003

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2017

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“…The drug is generally well tolerated and the most common adverse drug reactions are photosensitivity and esophagitis. Minocycline can cause a variety of pulmonary adverse effects, most notably organizing pneumonia and pulmonary infiltrates with eosinophilia [3] . Rarely, immune-mediated hypersensitivity syndromes have been observed such as serum sickness-like reactions, Steven-Johnson syndrome, autoimmune hepatitis, vasculitis and a lupus-like illness [4] , [5] .…”

Section: Introductionmentioning

confidence: 99%

Minocycline induced lupus with yellow colored chylous exudative pleural effusion

Starobin

Guller

Gurevich

et al. 2017

Respiratory Medicine Case Reports

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Ninety years old male was admitted to hospital due to breathlessness. The prominent findings were extensive blue-grey skin pigmentation and large left chylothorax. Drug induced lupus was diagnosed due to either minocycline chronic treatment or no alternative illness to explain his sub-acute disease. Minocycline therapy was stopped with gradual improvement of pleural effusion and skin discoloration. This case is the first presentation of minocycline induced lupus with chylothorax.

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Section: Introductionmentioning

confidence: 99%