Minireview on the Connections between the Neuropsychiatric and Dental Disorders: Current Perspectives and the Possible Relevance of Oxidative Stress and Other Factors

Abstract

Although the connections between neuropsychiatric and dental disorders attracted the attention of some research groups for more than 50 years now, there is a general opinion in the literature that it remains a clearly understudied and underrated topic, with many unknowns and a multitude of challenges for the specialists working in both these areas of research. In this way, considering the previous experience of our groups in these individual matters which are combined here, we are summarizing in this minireport the current status of knowledge on the connections between neuropsychiatric and dental manifestations, as well as some general ideas on how oxidative stress, pain, music therapy or even irritable bowel syndrome-related manifestations could be relevant in this current context and summarize some current approaches in this matter.

The Toothbrushing Effects on Surface Properties and Color Stability of CAD/CAM and Pressable Ceramic Fixed Restorations—An In Vitro Study

“…Microhardness results showed no significant difference between the tested groups before toothbrushing procedures: however, a significant difference was found between the tested ceramics after toothbrushing, which might be associated with the diversity of microstructures that could be affected by the toothbrushing procedure, as well as the abrasive particles in the tooth paste, which can cause microcracks and scratches on the surface of the ceramic materials, and, subsequently, can decrease its microhardness. Several aspects should be considered to better determine ceramics' hardness data, relating to surface properties, sizes, and boundaries of grain and crystalline phases [41] and oxidative stresses [42].…”

Natal and Neonatal Teeth: A Case Report and Mecanistical Perspective

“…In these cases if this residual tooth formation develops, a second surgical procedure is required [2]. In addition, lately there is a tendency for much clearer management in the cases of prematurely erupted teeth in newborns [36].…”

“…These aspects could be also relevant in the recent contexts regarding the connections between dental, neuropsychiatric and gastrointestinal processes, having for example oxidative stress and other complex factors in the center of these manifestations [36].…”

An Editorial-Approach Perspective on some of Our Preliminary Data Regarding the Neuropsychiatric and Gastrointestinal Manifestations in Covid-19

“…We previously showed on numerous occasions that the brain-gut axis and the so-called "second-brain" from the gut are very well correlated to most of the neuropsychiatric disorders [1][2][3][4][5][6][7][8][9][10].…”