Mining the Metabolic Capacity of Clostridium sporogenes Aided by Machine Learning
Huanrong Ouyang,
Zhao Xu,
Joshua Hong
et al.
Abstract:Anaerobes dominate the microbiota of the gastrointestinal (GI) tract, where a significant portion of small molecules can be degraded or modified. However, the enormous metabolic capacity of gut anaerobes remains largely elusive in contrast to aerobic bacteria, mainly due to the requirement of sophisticated laboratory settings. In this study, we employed an in‐silico machine learning platform, MoleculeX, to predict the metabolic capacity of a gut anaerobe, Clostridium sporogenes, against small molecules. Experi… Show more
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