Mining Human Microbiome for Therapeutics

Ghattargi, Vikas C.; Sape, Kamala; Kumbhare, Shreyas V.; Shouche, Yogesh S.

doi:10.1007/978-981-13-8315-1_18

Cited by 1 publication

(1 citation statement)

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“…Considering the significant role of the microbiome in overall health and its association with various disease states, it is only rational to explore the ways to target the gut microbiota as a therapeutic strategy. With emerging concepts and technological advances, the development of diagnostic, prognostic, and therapeutic tools to modulate the gut microbiota for the management of diseases seems feasible, however, challenges should be expected in this new field of scientific research (Ghattargi et al, 2019;Sarada et al, 2021). Since diet plays a major role in the constitution of the gut microbiome and is an influential modulator of the gut microbiota, the role of probiotics, prebiotics, postbiotics, and synbiotics has been investigated (Liu et al, 2022).…”

Section: Modulating the Gut Microbiomementioning

confidence: 99%

The Gut Microbiome: An Overview

Dimri¹,

Rizzo

2022

J Stud Res

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As a rapidly growing field of research over the past two decades, the Gut Microbiome has emerged as an important player with an integral role in human body functions. Its perturbed function correlates with several diseases such as diabetes, obesity, liver dysfunction, degenerative conditions, and neurological conditions. Studies utilizing the technological advancements with multi-omics methodologies continue to allow the detection and identification of gut microbes and provide mechanistic insights into their functioning. This review provides an overall understanding of the gut microbiome, its function, and communication with the brain and liver via the gut-brain axis and gut-liver axis. This review further discusses its role in some of the common disease states and some ways to potentially modulate the gut microbiome.

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Section: Modulating the Gut Microbiomementioning

confidence: 99%