Minimizing the Risk of Donor-Derived Events and Maximizing Organ Utilization Through Education and Policy Development

BackgroundThe purpose of this study was to understand how transplant infectious disease (TID) physicians assess a potential donor with known or suspected infection and describe posttransplant management.MethodsWe designed a survey of 10 organ offer scenarios and asked questions pertaining to organ acceptability for transplantation and management posttransplant. The survey was distributed to TID clinicians via transplant society listservs and email. Responses were recorded in REDCap, and descriptive statistics were employed.ResultsOne hundred thirteen infectious disease physicians responded to the survey, of whom 85 completed all cases. Respondents were generally in agreement regarding organ acceptability, although some divergence was seen when evaluating lungs from donors with influenza, tuberculosis, or multidrug‐resistant Acinetobacter infection. Posttransplant management showed more variation. Areas of optimization were identified: (1) Further understanding of where risk‐mitigation strategies within the donor offer process may improve donor acceptability and therefore organ utilization; (2) importance of recipient considerations in assessing degree of infectious risk; and (3) gaps in evidenced‐based data regarding optimal posttransplant management of recipients.ConclusionEvaluation of donor offers by TID clinicians is a complex process. Although the survey does not itself serve to make recommendations regarding best practices, it highlights areas where generation of data to inform acceptance and management practices may allow for improved organ utilization and recipient management. image

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Minimizing the Risk of Donor-Derived Events and Maximizing Organ Utilization Through Education and Policy Development

Cited by 4 publications

References 99 publications

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Challenging boundaries: Organ transplants from donors with Listeria central nervous system infections

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Minimizing risk while maximizing opportunity: The infectious disease organ offer process survey

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