Minimizing human intervention in intravenous admixture practice

Tribble, Dennis A.

doi:10.2146/ajhp090144

Cited by 4 publications

(4 citation statements)

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“…In addition, the vials, vehicle containers, syringes and needles are low-precision articles designed for human not robotic use. 12 Neither airborne contamination nor contamination by touch contamination or direct contact with contaminated surfaces was detected. None of the products prepared in the two different settings showed turbidity after the incubation period, thereby indicating no contamination with microorganisms.…”

Section: Media-fill Simulation Testsmentioning

confidence: 96%

Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes

Krämer

Federici

Kaiser

et al. 2014

J Oncol Pharm Pract

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Extensive media-fill tests simulating manual and automated preparation of ready-to-use cytotoxic injection solutions revealed the same level of sterility for both procedures. The results of supplemental environmental controls confirmed that the aseptic procedures are well controlled. As there was no difference in the microbial contamination rates of the media preparations depending on the extent of cleaning and disinfection of the robot, the results were used to adapt the respective standard operating procedures.

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Section: Media-fill Simulation Testsmentioning

confidence: 96%

Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes

Krämer

Federici

Kaiser

et al. 2014

J Oncol Pharm Pract

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“…Medications are packaged in containers that are "automation friendly" to permit the application of robotics to the selection, preparation, and distribution of medication packages at speeds and with certainty that cannot be achieved with human handling. 39…”

Section: Future State Current State Gap Analysismentioning

confidence: 99%

Opportunities and challenges related to technology in supporting optimal pharmacy practice models in hospitals and health systems

Siska

Tribble²

2011

American Journal of Health-System Pharmacy

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“…6 Several studies have demonstrated that the use of advanced technology contribute to enhance patient safety of the whole medication-use process from the prescription to the administration. [7][8][9][10][11][12][13][14][15][16] For some time now, the preparation of chemotherapy drugs has been centralized in specialized antineoplastic drugs units (UFA), that have to be located in the hospital pharmacies. UFAs aim is to ensure well-controlled aseptic procedures performed by highspecialized staff, improved quality controls, cost containment as well as optimized drug utilization.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Increasing pharmacy productivity and reducing medication turnaround times in an Italian comprehensive cancer center by implementing robotic chemotherapy drugs compounding

Capilli

Enrico

Federici

et al. 2021

J Oncol Pharm Pract

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Introduction The management of antineoplastic drugs used for chemotherapy is widely recognized as a high-risk activity. In 2018, our oncology pharmacy implemented workflow improvements to manage the growing workload due to the centralisation of activities from a hospital’s satellite pharmacy, moving towards automated compounding of antineoplastic drugs. The aim of this study was to determine the impact of the centralization on the productivity of the pharmacy department and evaluate the performances of the robotic chemotherapy drugs compounding. Material and methods Data were collected from the hospital information system and the workflow management software, and examined over a 3-year period (2017–2019). The total annual throughput in terms of doses prepared and patients treated and the Medication Turnaround Time (MTAT) were determined. Productivity and dosage accuracy were calculated for the robotic system. Results In 2018, the number of patients treated increased by 16.6%, consequently, the overall number of intravenous preparations compounded in the pharmacy increased by 17.2%. Regarding manual compounding, the total number of antineoplastic preparations decreased by about 2%. Investigational treatments manually compounded increased by about 27%, in contrast to the non-investigational treatments, which decreased by 9.4%. Regarding robotic compounding, the annual production increased by 50.4%. In 2018, the MTAT decreased about 24%. The dosage accuracy and precision of the total amount of doses were -1.1% and 1.2%, respectively. Conclusion This study indicates that in the effort to satisfy an ever-increasing workload, computerization and automation are essential instruments to maintain and ensuring high standards of quality.

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Minimizing human intervention in intravenous admixture practice

Cited by 4 publications

References 0 publications

Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes

Media-fill simulation tests in manual and robotic aseptic preparation of injection solutions in syringes

Opportunities and challenges related to technology in supporting optimal pharmacy practice models in hospitals and health systems

Increasing pharmacy productivity and reducing medication turnaround times in an Italian comprehensive cancer center by implementing robotic chemotherapy drugs compounding

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