“…Based on current understanding, this is the safest approach considering the fact that transmission via aerosol from the device has been verified. However, physically moving the device may involve significant structural and technical adjustments to the healthcare facilities, which will inevitably affect operational activities in and around the operating room [ 57 ].…”
Background: Mycobacterium chimaera (MC) is of recent origin and belongs to the large family of non-tuberculous mycobacteria. In recent years, it has shown a high infectious capacity via the aerosol produced by operating room equipment, such as heater–cooler units (HCU). The infection has a long latent period and high mortality rate. Genetic and epidemiological studies have shown that there is a clear link between the infection and a specific HCU model manufactured by LivaNova/Sorin. There is, therefore, a strong possibility that contamination occurs during device construction. The objective of this article is to describe the characteristics of this particular infection in view of the medico–legal implications on professional liability, specifically focusing on current evidence regarding contamination prevention. Methods: we have analyzed the clinical characteristics and data from the autopsic investigations performed on a patient who died as a result of MC infection, in addition to analyzing all pertinent recommendation documents available internationally. We searched for all articles in the literature available on MEDLINE between 1995 and 30 July 2020, using the search words “Mycobacterium chimaera”. We then analyzed those articles and reported only those that provide useful information regarding prevention techniques for containing dissemination and contamination. Results: the literature review produced 169 results that highlight the need to develop systems to mitigate and eliminate the risk of MC infection in operating rooms such as physical containment measures, e.g. device replacement, use of safe water, providing patients with information, and training healthcare professionals. Conclusions: from a medico–legal viewpoint, this particular situation represents a new frontier of professional liability, which includes manufacturers of electromedical equipment. In order to comprehend the true extent of this silent global epidemic, the development of an organic, preventative monitoring system is essential.
“…Based on current understanding, this is the safest approach considering the fact that transmission via aerosol from the device has been verified. However, physically moving the device may involve significant structural and technical adjustments to the healthcare facilities, which will inevitably affect operational activities in and around the operating room [ 57 ].…”
Background: Mycobacterium chimaera (MC) is of recent origin and belongs to the large family of non-tuberculous mycobacteria. In recent years, it has shown a high infectious capacity via the aerosol produced by operating room equipment, such as heater–cooler units (HCU). The infection has a long latent period and high mortality rate. Genetic and epidemiological studies have shown that there is a clear link between the infection and a specific HCU model manufactured by LivaNova/Sorin. There is, therefore, a strong possibility that contamination occurs during device construction. The objective of this article is to describe the characteristics of this particular infection in view of the medico–legal implications on professional liability, specifically focusing on current evidence regarding contamination prevention. Methods: we have analyzed the clinical characteristics and data from the autopsic investigations performed on a patient who died as a result of MC infection, in addition to analyzing all pertinent recommendation documents available internationally. We searched for all articles in the literature available on MEDLINE between 1995 and 30 July 2020, using the search words “Mycobacterium chimaera”. We then analyzed those articles and reported only those that provide useful information regarding prevention techniques for containing dissemination and contamination. Results: the literature review produced 169 results that highlight the need to develop systems to mitigate and eliminate the risk of MC infection in operating rooms such as physical containment measures, e.g. device replacement, use of safe water, providing patients with information, and training healthcare professionals. Conclusions: from a medico–legal viewpoint, this particular situation represents a new frontier of professional liability, which includes manufacturers of electromedical equipment. In order to comprehend the true extent of this silent global epidemic, the development of an organic, preventative monitoring system is essential.
“…14 An intensified cleaning and disinfection protocol succeeded in preventing detectable aerosolization of M. chimaera . 11,15 Therefore, the introduction of Puristeril and an increased frequency of water replacement changed our maintenance protocol.…”
Section: Discussionmentioning
confidence: 99%
“…To minimize patient exposure to Mycobacteria in the air droplets, it was suggested to completely remove the HCUs from the operating room. 11 To improve infection prevention, the companies introduced the use of Puristeril: its oxidation potential makes it a very efficient biocide and bleaching agent. This high reactivity means that it rapidly breaks down in the environment to benign oxygen, water and acetic acid, making it environmentally friendly, but hazardous to anyone exposed to it (class of danger H314 12 ).…”
Section: Mycobacterium Chimaera In Heater-cooler Units: New Technicalmentioning
confidence: 99%
“…To minimize patient exposure to Mycobacteria in the air droplets, it was suggested to completely remove the HCUs from the operating room. 11…”
Mycobacterium chimaera infections have mainly been associated with the heater-cooler unit (HCU) and, ultimately, linked to contaminated aerosols in the operation room. The contamination status of HCUs seems to be influenced by the maintenance, therefore, according to the manufacturer’s recommendations, peracetic acid (Puristeril) was introduced to increase HCU cleaning and disinfection protocol maintenance. Aerosol dispersion from Puristeril during maintenance can cause adverse effects to nearby workers. We aim to describe our technique to reduce the impact of Puristeril on operating room staff and to limit dispersion of its aerosol in the environment by performing the cleaning procedure through a closed circuit.
“…Additionally, NTM can grow over a very wide temperature range (15e45 C) and survive at 55e60 C [65]. Since decontamination measures often fail [41,91,92] and since intensified cleaning and disinfection might lead to device damage [36,106], facilities can either use other HCDs or they are strongly advised to separate HCDs from the OR room air volume by: (i) placing HCDs in dedicated utility rooms adjacent to the operating room (OR) [33,102,107,108] or (ii) placing them in encasings with controlled air extraction via a duct to the theatre exhaust conduit [41]. However, products such as encasings that are engineered and built by hospitals may alter the function of the HCD and the potential for such changes in function should be taken into consideration when implementing such interventions.…”
Section: Prevention Infection Control Measures and Reporting Obligationmentioning
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