Minimally invasive versus open living donors right hepatectomy: A systematic review and meta-analysis

Abdominal Organ Transplantation: Noteworthy Literature in 2021

“…Although biliary-related complications were higher, MIDRH was found to be superior to ODRH in intraoperative bleeding, postoperative hospital stay, and overall donor complications. 55 Gao and associates reported similar results in their meta-analysis. 56 Peng and colleagues specifically compared pure laparoscopic donor right hepatectomy vs ODRH on a total of 1,940 patients from 6 studies in their meta-analysis.…”

“…54 Zhao and colleagues performed a systematic review and meta-analysis comparing the short-term safety and efficacy of minimally invasive donor right hepatectomy (MIDRH) with open donor right hepatectomy (ODRH). 55 They identified 12 studies with a total of 1,755 donors who underwent right hepatectomy. Compared to ODRH, patients who underwent MIDRH had less bleeding (standardized mean difference [SMD] −.52, P < .001), shorter hospital stays (SMD -.58, P < .001), and lower overall postoperative donor complications (RR .74, P = .008).…”

Perioperative management of living donor liver transplantation: Part 2 – Donors

“…74,80,82,84,85,87 A recently published systematic review and meta-analysis compared the short-term safety and efficacy of minimally invasive donor right hepatectomy (MI Group) with open donor right hepatectomy (Open Group) using the 12 studies with a total of 1,755 donors. 88 After completing the parenchymal traction, the small hepatic veins to the right side of the liver are clipped, while more prominent veins are preserved. The liver graft is then wrapped in an endo-bag, and a Pfannenstiel incision is made.…”

“…PLRH has been demonstrated to produce similar surgical outcomes comparable to those of the open approach but with less adverse event profiles, including decreased pulmonary complications, less postoperative pain, and faster hospital discharge 74,80,82,84,85,87 . A recently published systematic review and meta‐analysis compared the short‐term safety and efficacy of minimally invasive donor right hepatectomy (MI Group) with open donor right hepatectomy (Open Group) using the 12 studies with a total of 1,755 donors 88 . Compared to Open Group, MI Group had less bleeding (standardized mean difference [SMD] ‐0.52, p < .001), shorter hospital stays (SMD ‐0.58, p < .001), and lower overall postoperative donor complications (RR 0.74, p = .008).…”

“…There were no statistically significant differences between MI Group and Open Group in postoperative liver function, rate of major complications and vascular complications of both donors and recipients, and overall postoperative complications. MI group was associated with prolonged operative times (SMD 0.74, p < .001), as well as a higher rate of biliary complications in donors (relative risk [RR] 2.26, p = .007) and recipients (RR 1.69, p < .001) 88 …”