Minimally Invasive Tissue Sampling Surveillance Alliance—Facilitating the Expansion of Pathology-Based Mortality Surveillance

Goco, Norman; McClure, Elizabeth M; Rakislova, Natalia; Bassat, Quique

doi:10.1093/cid/ciab827

Cited by 3 publications

(2 citation statements)

References 32 publications

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“…This may be due to the pathology unit's limited options or perinatal pathologists' limited availability to provide these specific services. Nonetheless, non-invasive or minimally invasive autopsies are being done in some LMICs with impressive uptakes since the formation of the MITS Surveillance Alliance in 2018 with funding from the Bill & Melinda Gates Foundation to expand pathology-based mortality surveillance and support the generation of improved CoD data (22). Successful MITS has been reported in Bangladesh, India, Kenya, Mali, Mozambique, Pakistan, and South Africa (23)(24)(25)(26)(27).…”

Section: Discussionmentioning

confidence: 99%

Perinatal autopsy in Ghana: Healthcare workers knowledge and attitude

Swarray‐Deen

Attah²,

Sefogah³

et al. 2022

Front. Glob. Womens Health

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BackgroundPerinatal mortality refers to stillbirths and early neonatal deaths. Stillbirth, the death of a foetus from 28 weeks or with a birth weight below 1,000 g, and early neonatal deaths, the death of a new-born within 24 h of delivery, are among the most distressing global health problems, with approximately 2 million stillbirths occurring annually. Although a post-mortem examination of the stillborn baby is essential for understanding and learning the cause of stillbirth, many couples decline the procedure. Sub-Saharan Africa has one of the highest stillbirth rates in the world, yet there is a dearth of studies on post-mortem uptake from the region.AimTo explore healthcare professionals' views and perceptions of perinatal autopsy in Ghana.MethodsMixed-method approach consisted of semi-structured interviews and an electronic cross-sectional survey to evaluate the views and perceptions of healthcare professionals at Korle-Bu Teaching Hospital on autopsy for stillbirths and early neonatal deaths. Descriptive quantitative data were summarised in frequencies and percentages, and statistical results and descriptions were tabulated and coded in terms of types of barriers. For the qualitative aspect, the audio-taped interviews were transcribed, themes generated, and direct quotes and descriptions were coded for all knowledge, beliefs, attitudes and practices concerning the barriers and facilitators for post-mortem.ResultsNinety-nine healthcare professionals participated. No participant had formal training regarding counselling for perinatal autopsy and 40% had “no idea” who is responsible for counselling and obtaining consent for a perinatal autopsy. Forty-four percent (44%) of the participants knew of only the “Conventional/ Full” autopsy and <4% were aware of less invasive methods of performing an autopsy. Qualitative data showed healthcare worker influence, religious and financial considerations impede the implementation of perinatal autopsies. Despite the low uptake of perinatal autopsies, interviews from healthcare workers suggest acceptance rates would improve if parents knew about different options, especially less invasive procedures.ConclusionAt Ghana's largest referral centre, perinatal autopsy counselling and uptake are at extremely low levels. Most healthcare professionals have little knowledge, skills, and capacity to advise parents regarding perinatal autopsies. Training is needed to update the workforce on recommended perinatal autopsy practices.

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Section: Discussionmentioning

confidence: 99%

Perinatal autopsy in Ghana: Healthcare workers knowledge and attitude

Swarray‐Deen

Attah²,

Sefogah³

et al. 2022

Front. Glob. Womens Health

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“…Currently, there is no literature available in the South Indian context regarding community perceptions of conventional diagnostic autopsy. An alternative novel method to CDA is Minimally Invasive Tissue Sampling (MITS) of organs to identify the cause of death (CoD), and it is helpful in low-resource settings where CDA is refused [8][9][10][11][12][13][14][15][16][17]. This technique was developed by the Barcelona Institute for Global Health (ISGlobal) in 2013, and is a low-cost method done by inserting a specialized needle in targeted organs and obtaining a biopsy, which is used for diagnosis [18,19].…”

mentioning

confidence: 99%

Community perceptions of postmortem examination and minimally invasive tissue sampling in neonates:a qualitative study in South India

Sreenivas,

Jaihind Jothikaran,

Lewis

et al. 2023

BMC Pregnancy Childbirth

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Background Postmortem examination is the gold standard for establishing the cause of death. Minimally Invasive Tissue Sampling (MITS) of organs is a novel approach that can be used as an alternative to postmortem examination. In this study, the community perceptions in two states in South India towards neonatal postmortem and the acceptance towards the MITS technique is studied. Methods In-depth interviews were conducted among the participants from Kerala and Karnataka to understand the perception towards postmortem and the acceptance of the novel MITS technique. The interviews were audio recorded, and a thematic analysis was done to identify the overarching themes and codes. Results The knowledge and attitude of participants on conventional and MITS postmortem techniques, reasons for refusal, and the need for raising awareness were identified in the study. Participants favored the MITS techniques as it was less disfiguring and less time-consuming. The major concerns for refusal of conventional postmortem were that the procedure was disfiguring, time-consuming, and caused emotional stress to the parents. Conclusions Participants favored the MITS approach over conventional postmortem as it caused less disfigurement and was conducive to the religious practice of burial of the body.

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