Minimally invasive surgery with adenocarcinoma of jejunum diagnosed pathologically before surgery: A case report

Lee, Sung Chul

doi:10.1016/j.ijscr.2021.01.061

Cited by 2 publications

(2 citation statements)

References 16 publications

(20 reference statements)

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“…DBE has a 85.9% positive rate of diagnosis opposed to the 72.9% of CT[ 30 ]. A case in 2021 was able to harness DBE to diagnose SBA presence and progression prior to surgery[ 31 ], allowing for early confirmation of peritoneal dissemination via laparoscopy prior to resection.…”

Section: Discussionmentioning

confidence: 99%

Small bowel adenocarcinoma in neoterminal ileum in setting of stricturing Crohn’s disease: A case report and review of literature

Karthikeyan¹,

Shen²,

Keyashian³

et al. 2023

World J Clin Cases

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BACKGROUND Small bowel adenocarcinomas (SBA) are rare malignancies with exceedingly low survival rates, with different presentation in Crohn’s disease (CD). CD-induced SBA poses diagnostic challenges given overlapping presentation with stricturing CD and lack of diagnostics for early detection. Moreover, guidance is lacking on the impact of recently approved therapeutics in CD on SBA management. Here, we aim to highlight the future of CD-induced SBA management and discuss the potential merit of balloon enteroscopy and genetic testing for earlier detection. CASE SUMMARY We report the case of a 60-year-old female with longstanding Crohn’s ileitis, presenting with acute obstructive symptoms attributed to stricturing phenotype. Her obstructive symptoms were refractory to intravenous (IV) steroids, with further investigation via computed tomography enterography not providing additional diagnostic yield. Ultimately, surgical resection revealed SBA in the neoterminal ileum, with oncologic therapy plan created. However, this therapy plan could not be initiated due to continued obstructive symptoms attributed to active CD. Ultimately, infused biologic therapy was initiated, but her obstructive symptoms continued to remain dependent on IV corticosteroids. Review of diagnostics by a multidisciplinary care team suggested metastatic disease in the peritoneum, lending to a shift in the goals of care to comfort. CONCLUSION With the diagnostic and therapeutic challenges of concurrent SBA and CD, multidisciplinary care and algorithmic management can optimize outcomes.

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Section: Discussionmentioning

confidence: 99%

Small bowel adenocarcinoma in neoterminal ileum in setting of stricturing Crohn’s disease: A case report and review of literature

Karthikeyan¹,

Shen²,

Keyashian³

et al. 2023

World J Clin Cases

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“…Small bowel adenocarcinoma (SBA) is a rare but increasing tumors of gastrointestinal malignancy, with diagnostic and therapeutic challenge. The clinical manifestations are unspecific, location resulting in delayed diagnosis, lack of a screening and prevention programme, SBA is diagnosed at an advanced stage, and very often at specimen analysis [1] . The annual incidence of the SBA accounts for only 1–3% of all gastrointestinal cancers and is 24–66 times lower than that of colorectal cancer [2] .…”

Section: Introductionmentioning

confidence: 99%

Small bowel adenocarcinoma a rare cause of upper gastrointestinal obstruction (a case report and literature review)

Bouali

Sylvestre

Benghait

et al. 2022

International Journal of Surgery Case Reports

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Introduction Small bowel adenocarcinoma is a rare but increasing disease. It poses both a diagnostic and therapeutic challange. Small bowel adenocarcinoma is a rare cause of small bowel obstruction. We present the case of a patient admitted to our emergency department for a bowel obstruction due to a mass of the jejunum and whose anatomopathological diagnosis was adenocarcinoma. Patient and method It is a 62-year-old woman with unparticular history, admitted to the emergency of visceral surgery of Ibn Rochd University Hospital for subocclusive syndrome evolving for one year, with early postprandial vomiting becoming stenosing two months ago. The abdominal CT scan showed thickening jejunal wall of 46 mm with upstream distension. She underwent a segmental bowel resection of 50 cm of small bowel with 3 cm stenotic mass located at 40 cm from the duodenojejunal angle. The pathophysiology revealed an invasive liberkhunian adenocarcinoma. The postoperative follow-up was simple, feeding allowed at D4 with discharge allowed at D6 and functional improvement at the time of the control performed three months after the intervention. Discussion Small bowel adenocarcinoma is rare and represents only 1–3% of all gastrointestinal cancers. The incidence of SBA is 24 to 66 times lower than that of colorectal cancer (CRC). Due to its non-specific clinical manifestation and less accessible location, SBA is diagnosed at an advanced stage, and often at specimen analysis. The treatment is resection and the overall survival is increased when diagnostic is early made. Conclusion Small bowel adenocarcinoma is a rare but increasing cause of gastrointestinal malignancy, being both a diagnostic and therapeutic challenge. In front of the occlusive syndrome of small bowel appearance, adenocarcinoma must be ruled out.

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Minimally invasive surgery with adenocarcinoma of jejunum diagnosed pathologically before surgery: A case report

Cited by 2 publications

References 16 publications

Small bowel adenocarcinoma in neoterminal ileum in setting of stricturing Crohn’s disease: A case report and review of literature

Small bowel adenocarcinoma in neoterminal ileum in setting of stricturing Crohn’s disease: A case report and review of literature

Small bowel adenocarcinoma a rare cause of upper gastrointestinal obstruction (a case report and literature review)

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