Minimally Invasive Surgery Versus Open Surgery for the Treatment of Rectal Gastrointestinal Stromal Tumor: A Propensity Score Matching Analysis of Short- and Long-Term Outcomes

Abstract

BackgroundsRectal GISTs are relatively rare and surgical resection is the potential curative treatment for rectal GISTs. However, limited studies addressing the outcomes of minimally invasive surgery for rectal GIST. MethodsA total of 32 rectal GIST patients were retrospective from January 2010 to December 2019 at Xiangya hospital Central South University. The demographic and clinicopathologic data were supplemented by our clinic and pathologic system. Selection bias was eliminated using the propensity score matching (PSM) methods ResultsAfter PSM, 22 patients were finally enrolled in our cohorts, with 11 patients in minimally invasive surgery (MIS) group and 11 patients in open surgery(OPEN) group randomly matched (1:1) by age, gender, body mass index, tumor size, tumor distance above the anal edge. MIS group recived a shorter operating time (108.45±31.56min vs 136.18±28.58min, P=0.043) and lesser blood less(67.27±54.97mL vs 194.55±115.96mL, P=0.004) than OPEN group during the operation. Besides, the MIS group seemed to gain a shorter time to resume borborygmus after operation, flatus passage, resuming oral diet, and hospital stay, but no significantly statistic difference(P＞0.05). Moreover, no differences in rate of 1-year, 3-year, and 5-year Progression Free Survival and overall survival was found between two groups.ConclusionCompared with open surgery, minimally invasive surgery benefits a shorter operating time and lesser blood less in operation in rectal GISTs. Moreover, similar oncologic outcome was found both in minimally invasive surgery and open surgery in rectal GISTs.