Minimally invasive interventional therapy for pain

Ye, Hua; Wu, Dan; Gao, Tian; Liu, Lu; He, Yong; Ding, Yong; Rao, Qiaoying; Wu, Qiaohong; Zhao, Zhong

doi:10.1016/j.jimed.2023.03.003

Cited by 2 publications

(3 citation statements)

References 61 publications

(71 reference statements)

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“…, urine drug testing, pill count), minimal invasive interventional ( e.g. , radiofrequency thermocoagulation, ablations, intrathecal drug delivery), 39 behavioral ( e.g. , diaries about craving), cognitive behavioral, and/or educational interventions for patients as well as healthcare providers.…”

Section: Discussionmentioning

confidence: 99%

“…37 Regardless of the exact definition, the high prevalence of different classes of pain medication clearly advocates the need for wellstructured management programs to promote medicines optimization (i.e., discuss misuse, abuse, aberrant drug behaviors, adherence, and nonadherence). 38 Interventions to optimize prescribed medicines and reduce their misuse in chronic nonmalignant pain nowadays involve clinical (e.g., urine drug testing, pill count), minimal invasive interventional (e.g., radiofrequency thermocoagulation, ablations, intrathecal drug delivery), 39 behavioral (e.g., diaries about craving), cognitive behavioral, and/or educational interventions for patients as well as healthcare providers. 38 The observed heterogeneity strongly supports the further implementation of a clear, consistent, and transparent approach to standardize medication optimization programs.…”

Section: Pain Medicinementioning

confidence: 99%

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Incidence and Prevalence of Pain Medication Prescriptions in Pathologies with a Potential for Chronic Pain

Goudman,

Moens,

Pilitsis

2023

Anesthesiology

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Background Heightened risks of dependence, addiction, anxiolytic effects, or prescription overdose death due to long-term use of pain medication have increased awareness about extended pain medication use in chronic pain populations. The goal of this study was to evaluate the incidence and prevalence of pain medication prescriptions from 2012 to 2022 in common pathologies with a potential for chronic pain. Methods A retrospective cohort study was conducted using electronic health records from TriNetX (Cambridge, Massachusetts) Global Collaborative Network. For 10 distinct cohorts (total n = 9,357,584 patients), pain medication prescriptions were extracted for five classes, namely nonsteroidal anti-inflammatory drug (NSAIDs) and acetaminophen, opioids, gabapentinoids, neuropathic mood agents, and muscle relaxants. Annual incidence and prevalence of each class of medication were evaluated for the past 11 yr. Results From 2012 to 2022, there was a significant increase in prescriptions of NSAIDs, except for patients with fibromyalgia, and persistent spinal pain syndrome (PSPS) type 2. Interestingly, over time, prescriptions of opioids in patients with complex regional pain syndrome, endometriosis, osteoarthritis, and PSPS type 2 increased, as did prescriptions of muscle relaxants for all cohorts except those with fibromyalgia. Incidence of prescriptions of neuropathic mood agents is high for patients with complex regional pain syndrome (both types) and PSPS type 2. Only for benzodiazepines did there seem to be a decline over the years, with a significantly decreased time trend in patients with complex regional pain syndrome type 1, fibromyalgia, and PSPS type 2. Conclusions During the last 11 yr, an increase in incidence of NSAIDs and acetaminophen, opioids, neuropathic agents, and muscle relaxants was observed. Only prescriptions of benzodiazepines significantly decreased over time in specific cohorts. Overall, patients with PSPS type 2 and complex regional pain syndrome (both types) consume a broad variety of pain medication classes. Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New

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Section: Discussionmentioning

confidence: 99%

Section: Pain Medicinementioning

confidence: 99%

Incidence and Prevalence of Pain Medication Prescriptions in Pathologies with a Potential for Chronic Pain

Goudman,

Moens,

Pilitsis

2023

Anesthesiology

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“…Interventional therapy has been considered as a very effective method of diagnosing and treating local lesions located in the cardiovascular system, nervous system, respiratory system, etc. − The success of intravascular interventional therapy depends on complex and delicate medical guide wires, which are roughly composed of the inner metal core wires from end to end, the spring coil sheaths using various metal materials at the head end, and the probable polymer coatings on the whole surface, with small overall diameters of <1 mm. The market demand for guide wires is significantly increasing all around the world.…”

Section: Introductionmentioning

confidence: 99%

Superhydrophilic and Antifriction Thin Hydrogel Formed under Mild Conditions for Medical Bare Metal Guide Wires

Yang,

Lin,

Shah

et al. 2023

ACS Appl. Mater. Interfaces

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Medical guide wires play a crucial role in the process of intravascular interventional therapy. However, it is essential for bare metal guide wires to possess both hydrophilic lubricity and coating durability, avoiding tissue damage caused by friction inside the blood vessel during the interventional procedure. Additionally, it is still a huge challenge for diverse metal materials to bind with polymer coatings easily. Herein, we present a hydrogel coating scheme and its preparation method for various wires under mild conditions for environmental protection purposes. The preparation process involves surface pretreatment, including lowtemperature heating and silanization, followed by a two-step dip coating and ultraviolet polymerization. The whole process leads to the formation of an interpenetrating cross-linked hydrogel network from the substrate to the surface section. This study confirms the superhydrophilicity and lubricity of three metal wires with the designed coating, especially reducing the friction significantly by ≥ 95%. The thin coating (average thickness <6.2 μm) demonstrates strong adhesion with various substrates and exhibits resistance to 25 or even 125 cycles of friction, indicating excellent stability and preventing easy detachment. The finally prepared composite nickel−titanium (NiTi) guide wire with stainless steel (SS) and platinum−tungsten (Pt−W) coils (overall diameter of ∼0.36 mm) shows satisfactory performance with a friction of 0.183 N for 25 cycles, meeting the clinical requirements (average friction ≤0.2 N) for interventional operation. These findings highlight the potential of this study in advancing the development of medical devices, particularly in the field of intravascular interventional therapy.

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Minimally invasive interventional therapy for pain

Cited by 2 publications

References 61 publications

Incidence and Prevalence of Pain Medication Prescriptions in Pathologies with a Potential for Chronic Pain

Incidence and Prevalence of Pain Medication Prescriptions in Pathologies with a Potential for Chronic Pain

Superhydrophilic and Antifriction Thin Hydrogel Formed under Mild Conditions for Medical Bare Metal Guide Wires

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