Minimally invasive biopsy in retroperitoneal tumors (Review)

Abstract

Minimally invasive biopsy procedures have proven over the years to be essential for obtaining a correct diagnosis of retroperitoneal tumors, that allows proper therapeutical conduct. These procedures offer valuable tissue fragments for histopathological examination, that permits the distinction between benign and malignant tumors, identifying the tumors that can benefit from neo-adjuvant treatments, such as chemotherapy or radiotherapy and those that have a direct surgical indication. We have searched the existing data regarding minimally invasive biopsy in retroperitoneal tumors using the PubMed database, in order to evaluate the role of this procedure in establishing a correct diagnosis, as well as to find out the risks of tumor cell seeding and local recurrence after needle biopsy. The risk of tumor cell seeding is very low (<2%) and in some cases, it is considered negligible (<0.5%). Compared to open biopsy, needle biopsy seems to be associated with a significantly lower risk of tumor cell seeding. According to the existing data, the incidence of needle track tumor cell seeding also depends on the histological type of the tumors. Image-guided retroperitoneal biopsy has proven to be low cost, accessible, and a reliable procedure (in terms of diagnostic accuracy), usually associating with a low rate of complications and a low risk of tumor seeding. Several authors have underlined the importance of the retroperitoneal approach and the association with a co-axial imaging technique in order to avoid potentially deadly complications. Contents 1. Introduction 2. Image-guided tumor biopsy 3. Biopsy techniques 4. Risk of tumor cell seeding using biopsy techniques 5. Conclusions

RETRACTED: Animal Models in Bladder Cancer

“…Other conventional imaging methods in animal studies include abdominal ultrasound, positron emission tomography-computerized tomography (PET-CT), and magnetic resonance imaging (MRI) and can be used for early tumor detection as early as 14 days after tumor inoculation in mice [ 136 ]. High-frequency and high-resolution intravesical ultrasound (HRUS) has been reported to demonstrate high sensitivity in monitoring tumor growth in orthotopic bladder cancer mouse models as a rapid, efficient, and comparatively inexpensive imaging modality [ 137 , 138 , 139 ]. Photoacoustic imaging (PAI) is a hybrid imaging modality that couples optical and ultrasound imaging in real time [ 140 ].…”

Multiple sclerosis, human herpesvirus 4 and thyroid collision tumor: A case report

“…Although vitamin D levels are associated with increased MS, the role of supplement doses should be further investigated (30). Difficulties in supporting differential diagnosis, or in the medical or surgical approach of patients with chronic neoplastic conditions are inherent (31)(32)(33)(34), but early detection and intervention increase survival and quality of life.…”

Psoas Muscle Abscess

“…Differential diagnosis should be made with retroperitoneal tumors [16,17], femoral hernia, enlarged inguinal nodes and iliac artery aneurysm [18].…”