Minimal Population Prevalence and Mortality of Coronavirus Disease 2019 in Healthcare Personnel

Abstract

Among 3926 healthcare personnel in a multisite healthcare system, the minimal population prevalence of coronavirus disease 2019 (COVID-19) was 4.4% (bootstrap 95% confidence interval [CI], 3.7%–5.0%), and the infection fatality rate was 0.6% (bootstrap 95% CI, 0.0%–1.7%). Rates reflected both local community prevalence and hospital exposures but not specifically exposure on COVID-19 units.

Concordance of SARS-CoV-2 RNA in Aerosols From a Nurses Station and in Nurses and Patients During a Hospital Ward Outbreak

“… 7 The frequency of positive samples was associated with the community prevalence of SARS-CoV-2 infection, consistent with the introduction of community-acquired SARS-COV-2 into the hospital setting. 7 , 8 , 9 …”

“…7 The frequency of positive samples was associated with the community prevalence of SARS-CoV-2 infection, consistent with the introduction of community-acquired SARS-COV-2 into the hospital setting. [7][8][9] These findings led to the hypothesis that nosocomial transmission of COVID-19 might be associated with the aerosolization of community-acquired SARS-CoV-2 within hospital spaces shared by HCP and patients. To test this hypothesis, we began to sample air in multiple shared hospital spaces before a looming surge in COVID-19 cases in the fall of 2020.…”

Seroprevalence in health care workers during the later phase of the second wave: Results of three hospitals in Serbia, prior to vaccine administration

“…The study described here was conducted at the end of the second wave which started earlier than in EU counties. Higher community prevalence is reflected in a higher prevalence in HCWs [22] . Therefore, a higher prevalence of seropositivity in Serbian HCWs compared to the EU at the same period, might be due to the second wave started and peaked in Serbia earlier than in other European countries.…”

Incidence of SARS-CoV-2 Infection in Health Care Workers After a Single Dose of mRNA-1273 Vaccine

“…Testing was triggered by policy for HCWs with symptoms, exposure, or for mandatory surveillance on selected units. 3 To account for the time required for the development of immunity, 4 we calculated 2 additional HRs excluding infections arising in the vaccinated group before days 8 and 15 following dose 1, respectively. Vaccine effectiveness was calculated as 100% × (1−HR).…”