Mini-craniotomy for intra-axial brain tumors: a comparison with conventional craniotomy in 306 patients harboring non-dural based lesions

Paolini, Sergio; Severino, Rocco; Mancarella, Cristina; Cardarelli, Giovanni; Ciavarro, Marco; Castelnuovo, Augusto Di; Iacoviello, Licia; Minniti, Giuseppe

doi:10.1007/s10143-022-01811-6

Cited by 3 publications

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“…Further detailed pre- and postoperative neuropsychological studies, or experimental studies investigating more cognitive aspects of interhemispheric transfer of information (e.g., tachistoscopic presentation of stimuli) are required to get deeper on how the surgical approaches, tumor location, and the associated ventriculomegaly affect the cognitive function or structural and functional reorganization. As well, here preliminary results are reported suggesting the importance of safer surgery on patients recovery ( 55 ). More researches are necessary to further explain how the white matter reorganization occurs and from which factors are driven.…”

Section: Discussionmentioning

confidence: 57%

Structural Brain Network Reorganization Following Anterior Callosotomy for Colloid Cysts: Connectometry and Graph Analysis Results

et al. 2022

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Introduction:The plasticity of the neural circuits after injuries has been extensively investigated over the last decades. Transcallosal microsurgery for lesions affecting the third ventricle offers an interesting opportunity to investigate the whole-brain white matter reorganization occurring after a selective resection of the genu of the corpus callosum (CC).MethodDiffusion MRI (dMRI) data and neuropsychological testing were collected pre- and postoperatively in six patients with colloid cysts, surgically treated with a transcallosal-transgenual approach. Longitudinal connectometry analysis on dMRI data and graph analysis on structural connectivity matrix were implemented to analyze how white matter pathways and structural network topology reorganize after surgery.ResultsAlthough a significant worsening in cognitive functions (e.g., executive and memory functioning) at early postoperative, a recovery to the preoperative status was observed at 6 months. Connectometry analysis, beyond the decrease of quantitative anisotropy (QA) near the resection cavity, showed an increase of QA in the body and forceps major CC subregions, as well as in the left intra-hemispheric corticocortical associative fibers. Accordingly, a reorganization of structural network topology was observed between centrality increasing in the left hemisphere nodes together with a rise in connectivity strength among mid and posterior CC subregions and cortical nodes.ConclusionA structural reorganization of intra- and inter-hemispheric connective fibers and structural network topology were observed following the resection of the genu of the CC. Beyond the postoperative transient cognitive impairment, it could be argued anterior CC resection does not preclude neural plasticity and may subserve the long-term postoperative cognitive recovery.

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Section: Discussionmentioning

confidence: 57%

Structural Brain Network Reorganization Following Anterior Callosotomy for Colloid Cysts: Connectometry and Graph Analysis Results

et al. 2022

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Radiotherapy of high-grade gliomas: dealing with a stalemate

Frosina

2023

Critical Reviews in Oncology/Hematology

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The surgical management of diffuse gliomas: Current state of neurosurgical management and future directions

et al. 2023

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After recent updates to the World Health Organization pathological criteria for diagnosing and grading diffuse gliomas, all major North American and European neuro-oncology societies recommend a maximal safe resection as the initial management of a diffuse glioma. For neurosurgeons to achieve this goal, the surgical plan for both low- and high-grade gliomas should be to perform a supramaximal resection when feasible based on pre-operative imaging and the patient’s performance status, utilizing every intraoperative adjunct to minimize post-operative neurological deficits. While the surgical approach and technique can vary, every effort must be taken to identify and preserve functional cortical and subcortical regions. In this summary statement on the current state of the field, we describe the tools and technologies that facilitate the safe removal of diffuse gliomas and highlight intra-operative and post-operative management strategies to minimize complications for these patients. Moreover, we discuss how surgical resections can go beyond cytoreduction by facilitating biological discoveries and improving the local delivery of adjuvant chemo- and radiotherapies.

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Mini-craniotomy for intra-axial brain tumors: a comparison with conventional craniotomy in 306 patients harboring non-dural based lesions

Cited by 3 publications

References 50 publications

Structural Brain Network Reorganization Following Anterior Callosotomy for Colloid Cysts: Connectometry and Graph Analysis Results

Structural Brain Network Reorganization Following Anterior Callosotomy for Colloid Cysts: Connectometry and Graph Analysis Results

Radiotherapy of high-grade gliomas: dealing with a stalemate

The surgical management of diffuse gliomas: Current state of neurosurgical management and future directions

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