Mineralocorticoid Receptor Antagonism by Eplerenone and Arterial Inflammation in HIV
Suman Srinivasa,
Shady Abohashem,
Allie R. Walpert
et al.
Abstract:ImportanceThe risk for atherosclerotic disease is increased 1.5- to 2.0-fold among persons with HIV (PWH). Increased activation of the renin-angiotensin-aldosterone system may contribute to increased arterial inflammation in this population.ObjectiveTo determine the effects of eplerenone on arterial inflammation among well-treated PWH without known cardiovascular disease (CVD).Design, Setting, and ParticipantsWell-treated PWH who participated in the double-blinded, placebo-controlled, Mineralocorticoid Recepto… Show more
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