Mindfulness Meditation Alleviates Fibromyalgia Symptoms in Women: Results of a Randomized Clinical Trial

Abstract

34628811).

Mindfulness Meditation for Chronic Pain: A Systematic Review

“…However, using the trim and fill method to correct for this bias yielded an estimate identical to the original pooled result The effect was very similar when nine poor quality studies were excluded from analysis (SMD 0.2; CI 0.03, 0.38; not displayed); heterogeneity was moderate (I 2 43.8%). Eleven RCTs followed study participants more than 12 weeks (median: 20 weeks; range: 16-60 weeks) Cash et al, 2015;Dowd et al, 2015;Morone et al, 2009;Omidi and Zargar, 2014;Parra-Delgado and Latorre-Postigo, 2013;Rahmani and Talepasand, 2015;Gaylord et al, 2011). Figure 3.4 shows that there is an effect of meditation on pain for participants in six of these studies but not overall (SMD 0.37; C −0.01, 0.74; 11 RCTs, I 2 74.7%) Omidi and Zargar, 2014;Parra-Delgado and Latorre-Postigo, 2013;Rahmani and Talepasand, 2015;Gaylord et al, 2011).…”

“…The median short-term follow-up time was eight weeks (range 4-12 weeks). Figure 3.3 shows a positive effect of meditation on pain from 0-12 weeks in 17 studies (Brown and Jones, 2013;Cash et al, 2015;Cathcart et al, 2014;Esmer et al, 2010;Morone, Greco, and Weiner, 2008;Omidi and Zargar, 2014;Plews-Ogan et al, 2005;Teixeira, 2010;Wells et al, 2014;Zautra et al, 2008;Parra-Delgado and LatorrePostigo, 2013;Rahmani and Talepasand, 2015;Gaylord et al, 2011;Ljotsson, Falk, et al, 2010), which was statistically significant in five studies Omidi and Zargar, 2014;Wells et al, 2014;Rahmani and Talepasand, 2015;Gaylord et al, 2011). The pooled analysis of all 24 RCTs showed a significant positive effect (SMD 0.27; CI 0.04, 0.50; 24 RCTs; I 2 64.6%).…”

“…Seven studies obtained a "good" quality rating Fogarty et al, 2015;Ljotsson, Falk, et al, 2010;Parra-Delgado and Latorre-Postigo, 2013;Zautra et al, 2008). Ten studies were judged to be of fair quality, primarily due to being unclear in some aspects of the methods (Cash et al, 2015;Davis and Zautra, 2013;Day et al, 2014;Dowd et al, 2015;Gaylord et al, 2011;la Cour and Petersen, 2015;Morone, Greco, and Weiner, 2008;Wells et al, 2014). Eleven studies were judged to be poor; eight of these were primarily due to issues with completeness of reporting outcome data, such as inadequate or missing ITT analysis or less than 80-percent follow-up Brown and Jones, 2013;Cathcart et al, 2014;Esmer et al, 2010;Meize-Grochowski et al, 2015;Morone et al, 2009;Omidi and Zargar, 2014;PlewsOgan et al, 2005).…”

“…Pain scales and comparators varied from study to study (Astin et al, 2000;Brown and Jones, 2013;Cash et al, 2015;Cathcart et al, 2014;Davis and Zautra, 2013;Day et al, 2014;Dowd et al, 2015;Esmer et al, 2010;la Cour and Petersen, 2015;Meize-Grochowski et al, 2015;Morone, Greco, and Weiner, 2008;Morone et al, 2009;Omidi and Zargar, 2014;Plews-Ogan et al, 2005;Teixeira, 2010;Wells et al, 2014;Zautra et al, 2008;Parra-Delgado and Latorre-Postigo, 2013;Rahmani and Talepasand, 2015;Gaylord et al, 2011;Ljotsson, Falk, et al, 2010). The median follow-up time was 12 weeks, with a range of four to 60 weeks.…”

“…A meta-regression found that treatment effects did not differ significantly when TAU was used as a comparator versus all other comparators. Among the eight RCTs that compared mindfulness meditation to a passive control (either intervention or a waitlist for the primary intervention) (Cash et al, 2015;Cathcart et al, 2014;Day et al, 2014;la Cour and Petersen, 2015;Meize-Grochowski et al, 2015;Morone, Greco, and Weiner, 2008;Rahmani and Talepasand, 2015), one showed a significant effect of meditation on pain (Rahmani and Talepasand, 2015). The pooled effect (displayed in Figure 3.6) was not significant (SMD 0.28; CI −0.46, 1.02; 8 RCTs; I 2 76.5%); considerable heterogeneity was detected.…”