Mindfulness group therapy in primary care patients with depression, anxiety and stress and adjustment disorders: Randomised controlled trial

Sundquist, Jan; Lilja, Åsa; Palmér, Karolina; Memon, Ashfaque A.; Wang, Xiao; Johansson, Lars-Åke; Sundquist, Kristina

doi:10.1192/bjp.bp.114.150243

Cited by 94 publications

(110 citation statements)

References 40 publications

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“…The RCT included a group of patients with depression, anxiety or stress, and adjustment disorder. A detailed description of the study design is provided in our previous article [34]. The overall aim of the RCT was to compare the effect of a structured mindfulness-based group therapy program with treatment as usual (mostly individual cognitive behavioral therapy (CBT)) [53].…”

Section: Study Subjects and Sample Collectionmentioning

confidence: 99%

“…A total of 135 patients met the inclusion criteria for MADRS-S, 118 for HADS-A, 159 for HADS-D, and 111 for PHQ-9. The rationale for using multiple scales to assess symptoms of depression and anxiety was that different scales are used in clinical practices worldwide [34]. Eligible patients had a clinical diagnosis of depression, anxiety or stress, and adjustment disorder, according to the International Classification of Diseases (ICD)-10 criteria.…”

Section: Study Subjects and Sample Collectionmentioning

confidence: 99%

“…The present study builds on a previously published randomized controlled trial by our group, where we included patients with depression/anxiety from 16 primary health care centers [34] in Sweden in order to compare the effects of mindfulness treatment with treatment as usual on depressive/anxiety symptoms. In the present study, we hypothesized that patients with depression/anxiety would experience a significant change in plasma miRNAs after an 8-week treatment and that there would be an association between plasma miRNA levels and symptoms of depression/anxiety at baseline.…”

Section: Introductionmentioning

confidence: 99%

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Section: Study Subjects and Sample Collectionmentioning

confidence: 99%

Section: Study Subjects and Sample Collectionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Circulating microRNA-144-5p is associated with depressive disorders

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“…9 An important point to be noted in our review was the inclusion of articles describing internet-based mindfulness treatment programs for anxiety. The remote delivery of these programs did not appear to decrease the effectiveness of the mindfulness interventions,…”

Section: Discussionmentioning

confidence: 99%

“…The group treatment was based on two mindfulness-based therapies, MBSR and MBCT. 9 A trial study evaluated the efficacy of an internetbased mindfulness treatment program for anxiety. The study randomly assigned 91 subjects diagnosed with social anxiety disorder, generalized anxiety disorder, panic disorder, or anxiety disorder to a mindfulness treatment group (MTG) or a discussion forum control group (CG).…”

Section: Introductionmentioning

confidence: 99%

Mindfulness in mood and anxiety disorders: a review of the literature

Rodrigues¹,

Nardi²,

Levitan

2017

Trends Psychiatry Psychother.

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Trends in Psychiatry and Psychotherapy Review ArticleResumo Introdução: O objetivo deste estudo foi fazer uma revisão da literatura abrangendo o uso das diferentes abordagens da terapia baseada em mindfulness no tratamento dos transtornos de humor e ansiedade, incluindo suas habilidades e sua relação com a regulação emocional e com o medo da avaliação negativa. Métodos: Uma revisão de literatura foi realizada através de busca pelas bases científicas PubMed e PsycINFO, com as seguintes palavras-chave: mindfulness, transtornos do humor e transtornos de ansiedade. A pesquisa abrangeu os últimos 10 anos. A busca resultou em 532 artigos, sendo 24 selecionados e 16 incluídos nesta revisão. Resultados: Foram revisados seis artigos sobre programa de redução de estresse baseado em mindfulness, quatro artigos sobre terapia cognitiva baseada em mindfulness, e três sobre medo da avaliação negativa e regulação emocional. Todos os artigos abordaram mindfulness com relação aos transtornos de humor e ansiedade Conclusão: A literatura nessa área sugere que mindfulness é uma estratégia eficaz no tratamento dos transtornos de humor e ansiedade e é eficaz no protocolo de terapia em diferentes formatos, incluindo virtual. O uso de mindfulness continua a se expandir nos modelos científicos. Descritores: Mindfulness, transtornos do humor e transtornos ansiosos. AbstractIntroduction: The objective of this study was to conduct a review of the literature covering the use of different mindfulnessbased therapy approaches in treatment of mood and anxiety disorders, including mindfulness skills and mindfulness linked to emotional regulation and fear of negative appraisal. Methods: A review was conducted of literature identified by searching the scientific databases PubMed and PsycINFO with the following keywords: mindfulness, mood disorders, and anxiety disorders. The search covered the past 10 years. The search returned 532 articles, 24 were selected, their full texts were read, and 16 were included in this review. Results: Six articles about mindfulness-based stress reduction, four about mindfulness-based cognitive therapy, and three about fear of negative appraisal and emotional regulation were reviewed. All of the articles covered mindfulness in relation to mood and anxiety disorders. Conclusions: The literature in this field suggests that mindfulness is an effective strategy for the treatment of mood and anxiety disorders and is effective in therapy protocols with different structures including virtual modalities. Use of mindfulness in scientific models continues to expand.

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Anxiety Screening

O’Connor

Henninger

Perdue

et al. 2023

JAMA

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ImportanceAnxiety is commonly seen in primary care and associated with substantial burden.ObjectiveTo review the benefits and harms of screening and treatment for anxiety and the accuracy of instruments to detect anxiety among primary care patients.Data SourcesMEDLINE, PsychINFO, Cochrane library through September 7, 2022; references of existing reviews; ongoing surveillance for relevant literature through November 25, 2022.Study SelectionEnglish-language original studies and systematic reviews of screening or treatment compared with control conditions and test accuracy studies of a priori–selected screening instruments were included. Two investigators independently reviewed abstracts and full-text articles for inclusion. Two investigators independently rated study quality.Data Extraction and SynthesisOne investigator abstracted data; a second checked accuracy. Meta-analysis results were included from existing systematic reviews where available; meta-analyses were conducted on original research when evidence was sufficient.Main Outcomes and MeasuresAnxiety and depression outcomes; global quality of life and functioning; sensitivity and specificity of screening tools.ResultsOf the 59 publications included, 40 were original studies (N = 275 489) and 19 were systematic reviews (including ≈483 studies [N≈81 507]). Two screening studies found no benefit for screening for anxiety. Among test accuracy studies, only the Generalized Anxiety Disorder (GAD) GAD-2 and GAD-7 screening instruments were evaluated by more than 1 study. Both screening instruments had adequate accuracy for detecting generalized anxiety disorder (eg, across 3 studies the GAD-7 at a cutoff of 10 had a pooled sensitivity of 0.79 [95% CI, 0.69 to 0.94] and specificity of 0.89 [95% CI, 0.83 to 0.94]). Evidence was limited for other instruments and other anxiety disorders. A large body of evidence supported the benefit of treatment for anxiety. For example, psychological interventions were associated with a small pooled standardized mean difference of −0.41 in anxiety symptom severity in primary care patients with anxiety (95% CI, −0.58 to −0.23]; 10 RCTs [n = 2075]; I2 = 40.2%); larger effects were found in general adult populations.Conclusions and RelevanceEvidence was insufficient to draw conclusions about the benefits or harms of anxiety screening programs. However, clear evidence exists that treatment for anxiety is beneficial, and more limited evidence indicates that some anxiety screening instruments have acceptable accuracy to detect generalized anxiety disorder.

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Mindfulness group therapy in primary care patients with depression, anxiety and stress and adjustment disorders: Randomised controlled trial

Abstract: Mindfulness-based group therapy was non-inferior to treatment as usual for patients with depressive, anxiety or stress and adjustment disorders.

Cited by 94 publications

References 40 publications

Circulating microRNA-144-5p is associated with depressive disorders

Circulating microRNA-144-5p is associated with depressive disorders

Mindfulness in mood and anxiety disorders: a review of the literature

Anxiety Screening

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