Families of children with disabilities often experience high levels of stress associated with taking care of a child with disability. The perceived stress by the caregivers may often lead to negative outcomes in day-to-day functioning for caregivers themselves as well as the child. Mindfulness as an element of consciousness has been acknowledged to promote positivity and well-being among individuals. It is a mental state achieved by focusing one's awareness on the present moment, while calmly acknowledging and accepting one's feelings, thoughts, and bodily sensations. This chapter focuses on the application of mindfulness-based therapies for caregivers (parents) of children with cerebral palsy. This chapter also entails in detail therapeutic techniques like Mindfulness-Based Stress Reduction (MBSR), its in-depth description, background, and applications as an effective approach for the intervention of caregivers.