“…Nevertheless, many uncertain or unknown parameters enter in the modeling of internal processes in stars (poorly known nuclear reaction rates, modeling of mixing processes, wind mass loss rates, etc.). Exploring the parameter space for single star evolution is a challenging task still being actively pursued (e.g., Woosley, 2017;Renzo et al, 2017;Sukhbold et al, 2018;Woosley, 2019;Farmer et al, 2019, for recent studies of single massive stars). When considering the evolution of two stars born together in a binary, i.e., the standard for massive stars, the number of dimensions of the parameter space increases very rapidly: not only the evolution of a massive binary system depends on the two initial masses of the stars, but also their initial orbital period and, possibly, eccentricity.…”