Mimics of vasculitis

Maningding, Ernest; Kermani, Tanaz A.

doi:10.1093/rheumatology/keaa495

Cited by 11 publications

(12 citation statements)

References 102 publications

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“…Therefore, it is essential to rule out any differential diagnoses. To effectively diagnose vasculitis, including PAN, various critical diseases, such as sepsis, infectious endocarditis (IE), and malignancies, including IVL, must be ruled out [ 7 , 8 ]. Vasculitis occurs mainly in older patients, and intensive investigations are limited because of frailty and self-agism [ 9 , 10 ].…”

Section: Discussionmentioning

confidence: 99%

“…Vasculitis occurs mainly in older patients, and intensive investigations are limited because of frailty and self-agism [ 9 , 10 ]. The minimal requirements for ruling out differential diagnoses are blood cultures, systemic CT scans with contrast, and dermal biopsies [ 7 , 8 ]. Four blood cultures were used to rule out persistent bacteremia, including infectious endocarditis (IE) [ 11 ].…”

Section: Discussionmentioning

confidence: 99%

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Comprehensive Management of Vasculitis and Suspected Polyarteritis Nodosa in an Older Patient

Ohta¹,

Sano²

2023

Cureus

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Polyarteritis nodosa (PAN) is a rare autoimmune disease that affects medium-sized arteries and causes inflammation and damage to the blood vessel walls. Testicular pain is an uncommon symptom of PAN but can occur in rare cases. This specific symptom may be useful in diagnosing older patients with limited tissue access because of their vulnerability and high risk for biopsy complications. We report the case of a 78-yearold male patient with progressive fatigue and walking difficulty. After ruling out various forms of vasculitis and malignancy, we diagnosed the patient with PAN and intensively treated him with rituximab, which successfully cured his symptoms. This case report highlights the importance of intensively ruling out possible diagnoses mimicking vasculitis and treating vasculitis with a tentative diagnosis of PAN in older patients in rural hospitals. The progressive clinical course of vasculitis may devastate older patients' activities of daily living (ADLs). PAN may particularly affect older patients with possible hepatitis B infections. Thus, shared decision-making and prompt intensive treatment should be considered.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Comprehensive Management of Vasculitis and Suspected Polyarteritis Nodosa in an Older Patient

Ohta¹,

Sano²

2023

Cureus

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“…In addition, the recognition of vasculitis mimics is also important. For example, thrombotic and hypercoagulable conditions in patients can mimic medium and small vessel vasculitis, presenting as purpura ( 26 , 27 ). In this case, the boy had no evidence of infection or history that supported simulated vasculitis.…”

Section: Discussionmentioning

confidence: 99%

Purpura with regular shape in an adolescent: Beware of dermatitis artefacta

Chen

Li²,

Lu³

2022

Front. Pediatr.

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BackgroundPurpura is common in pediatric patients, mostly diagnosed as IgA-related vasculitis (Henoch–Schönlein purpura), idiopathic thrombocytopenic purpura (ITP), and thrombotic thrombocytopenic purpura (TTP). However, in some cases, for example, cases with dermatitis artefacta, it could puzzle a physician or pediatrician for a long time, with great challenges in diagnosis.Case presentationWe present the case of a 13-year-old boy with recurrent painful purpura on both upper limbs. The physical exam was unremarkable, except for right blepharoptosis and scars from burns. The diagnostic tests were normal. Through repeated communication, the patient was finally diagnosed as having dermatitis artefacta, accompanied by underlying psychological problems.ConclusionsBefore dermatitis artefacta was diagnosed, we spent a lot of money and effort on the diagnosis. Therefore, in order to determine the diagnosis as soon as possible and save on unnecessary medical expenses, we propose a rapid process for the diagnosis of purpura of dermatitis artefacta in children.

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“…A few selected mimics are discussed individually below. A detailed discussion about vasculitis mimics can be found elsewhere [ 134 •, 135 ].…”

Section: Vasculitis Mimics and Important Other Disordersmentioning

confidence: 99%

Spectrum of Large and Medium Vessel Vasculitis in Adults: Primary Vasculitides, Arthritides, Connective Tissue, and Fibroinflammatory Diseases

Seitz

Pop

et al. 2022

Curr Rheumatol Rep

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Purpose of Review To provide a comprehensive overview of the spectrum of large and medium vessel vasculitis in adults with primary vasculitides, arthritides, connective tissue, and fibroinflammatory diseases as well as vasculitis mimics, for an efficient differential diagnosis and initial diagnostic approach. Recent Findings Imaging has had a tremendous impact on the diagnosis of medium to large vessel vasculitis, now often replacing histopathologic confirmation and identifying new disease manifestations (e.g., intracranial disease in giant cell arteritis; vascular manifestations of IgG4-related disease). Novel diseases or syndromes involving blood vessels have been described (e.g., VEXAS-Syndrome with polychondritis). The use of the terms “medium” or “large” vessel varies considerably between medical specialties. Summary The differential diagnosis of large and medium vessel vasculitis is becoming increasingly complex as new entities or disease manifestations of known inflammatory rheumatic diseases are regularly identified. A more precise and widely recognized definition of the vessel sizes would make future research more comparable.

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Mimics of vasculitis

Cited by 11 publications

References 102 publications

Comprehensive Management of Vasculitis and Suspected Polyarteritis Nodosa in an Older Patient

Comprehensive Management of Vasculitis and Suspected Polyarteritis Nodosa in an Older Patient

Purpura with regular shape in an adolescent: Beware of dermatitis artefacta

Spectrum of Large and Medium Vessel Vasculitis in Adults: Primary Vasculitides, Arthritides, Connective Tissue, and Fibroinflammatory Diseases

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