Milwaukee shoulder (and knee) syndrome

Santiago, Tânia; Coutinho, Margarida; Malcata, Armando; Silva, José António Pereira da

doi:10.1136/bcr-2013-202183

Cited by 8 publications

(3 citation statements)

References 3 publications

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“…Joint fluid shows serohematic or hemorrhagic appearance and non-inflammatory pattern (usually ＜1,000/mL leukocyte) [4]. The radiologic examination shows narrowing of the glenohumeral joint, bone sclerosis, destruction of subchondral bone and osteophytes, capsular and soft tissue calcification, and intraarticular loose bodies [4][5][6]. MRI additionally shows rotator cuff tears and cartilage thinning [7].…”

Section: Discussionmentioning

confidence: 99%

Very Rapidly Progressive Shoulder Arthropathy with Complete Destruction of the Humeral Head

et al. 2019

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Milwaukee shoulder syndrome (MSS) is a rare disease in which joints are destroyed and occurs mainly in elderly women. We describe rapidly progressive MSS with complete destruction of the shoulder joint within 2 months. An 80-year-old woman visited the outpatient clinic with shoulder pain for 2 weeks. rotator cuff tear arthropathy was diagnosed, and nonsteroidal anti-inflammatory drugs were prescribed. Two months later, her shoulder pain worsened without trauma. Shoulder swelling and tenderness, and arm lifting inability were observed. Complete humeral head disruption was observed by radiography. We diagnosed MSS based on the presence of serohematic and noninflammatory joint effusion, periarticular calcific deposits, and rapid joint destruction, and initiated conservative treatment. When initially treating elderly patients with shoulder arthropathy, it is advisable to perform short-term follow-up and to consider the possibility of crystal-induced arthropathy.

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Section: Discussionmentioning

confidence: 99%

Very Rapidly Progressive Shoulder Arthropathy with Complete Destruction of the Humeral Head

et al. 2019

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“…McCarty et al [ 77 ] formally identified the condition after encountering four elderly female patients with similar symptoms of shoulder joint arthropathy, rotator cuff defects, and large joint effusions . MSS is a rare disease linked to BCP crystal associated joint destruction [ 78 ]. It affects the shoulder joint, commonly causing rotor cuff defects in the absence of injury (bilaterally in 60% of cases), and gives an increased risk of OA in other joints, especially the knee [ 79 ].…”

Section: Rare Forms Of Crystal Deposition Diseasesmentioning

confidence: 99%

“Lessons from Rare Forms of Osteoarthritis”

et al. 2021

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Osteoarthritis (OA) is one of the most prevalent conditions in the world, particularly in the developed world with a significant increase in cases and their predicted impact as we move through the twenty-first century and this will be exacerbated by the covid pandemic. The degeneration of cartilage and bone as part of this condition is becoming better understood but there are still significant challenges in painting a complete picture to recognise all aspects of the condition and what treatment(s) are most appropriate in individual causes. OA encompasses many different types and this causes some of the challenges in fully understanding the condition. There have been examples through history where much has been learnt about common disease(s) from the study of rare or extreme phenotypes, particularly where Mendelian disorders are involved. The often early onset of symptoms combined with the rapid and aggressive pathogenesis of these diseases and their predictable outcomes give an often-under-explored resource. It is these “rarer forms of disease” that William Harvey referred to that offer novel insights into more common conditions through their more extreme presentations. In the case of OA, GWAS analyses demonstrate the multiple genes that are implicated in OA in the general population. In some of these rarer forms, single defective genes are responsible. The extreme phenotypes seen in conditions such as Camptodactyly Arthropathy-Coxa Vara-pericarditis Syndrome, Chondrodysplasias and Alkaptonuria all present potential opportunities for greater understanding of disease pathogenesis, novel therapeutic interventions and diagnostic imaging. This review examines some of the rarer presenting forms of OA and linked conditions, some of the novel discoveries made whilst studying them, and findings on imaging and treatment strategies.

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“…This rare arthropathy exhibits a rapidly progressive joint destruction, often affects older women, and is connected with rotator cuff tears [ 61 ]. Synovial fluid aspiration yields a mixture of calcium crystals (predominantly hydroxy-apatite) and sero-hematic synovial fluid with low leucocyte counts [ 62 ].…”

Section: Bcp and Mixed Crystal Diseasementioning

confidence: 99%

Imaging of Joints and Bones in Autoinflammation

Ziegeler

Eshed

Diekhoff

et al. 2020

JCM

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Autoinflammatory disorders are commonly characterized by seemingly unprovoked systemic inflammation mainly driven by cells and cytokines of the innate immune system. In many disorders on this spectrum, joint and bone involvement may be observed and imaging of these manifestations can provide essential diagnostic information. This review aimed to provide a comprehensive overview of the imaging characteristics for major diseases and disease groups on the autoinflammatory spectrum, including familial Mediterranean fever (FMF), Behçet disease (BD), crystal deposition diseases (including gout), adult-onset Still’s disease (AoSD), and syndromatic synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO)/chronic recurrent multifocal osteomyelitis (CRMO). Herein, we discuss common and distinguishing imaging characteristics, phenotypical overlaps with related diseases, and promising fields of future research.

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Milwaukee shoulder (and knee) syndrome

Cited by 8 publications

References 3 publications

Very Rapidly Progressive Shoulder Arthropathy with Complete Destruction of the Humeral Head

Very Rapidly Progressive Shoulder Arthropathy with Complete Destruction of the Humeral Head

“Lessons from Rare Forms of Osteoarthritis”

Imaging of Joints and Bones in Autoinflammation

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