Milk somatic cell derived transcriptome analysis identifies regulatory genes and pathways during lactation in Indian Sahiwal cattle (Bos indicus)

Ahlawat, Sonika; Vijh, R. K.; Sharma, Anju; Sharma, Upasna; Girdhar, Yashila; Kaur, Manpreet; Chhabra, Pooja; Kumar, Ashok; Arora, Reena

doi:10.1007/s11033-020-05764-1

Cited by 3 publications

(1 citation statement)

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“…During the lactation period expression of milk somatic cells may help to identify more essential genes that are involved in milk production and in its formation. Mammary transcriptome in dairy cows revolved around the cattle's health and milk production [ 9 ]. Availability of gene expression data, i.e., microarray and RNA-seq, and Bioinformatics resources for functional genomics make it feasible to perform functional genomics in a more advanced and precise manner [ 10 ].…”

Section: Introductionmentioning

confidence: 99%

Identification and annotation of milk associated genes from milk somatic cells using expression and RNA-seq data

Krishna¹

2022

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It is of interest to identify and annotate milk associated genes using expression profiling and RNA-Seq data from milk somatic cells. RNA-Seq data was pre-processed and mapping was done to identify differentially expressed genes (DEG). The functional insights about the up and down regulated genes were gleaned using the protein-protein interaction Network in the STRING database followed by CytoHubba analysis in Cytoscope. Gene ontology, annotation and pathway enrichment was completed using ShinyGO, David tool and QTL analysis. These analysis shows that 21 genes are linked with the secretion of milk.

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Section: Introductionmentioning

confidence: 99%